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    CG4743 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43101, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG4743provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039357
    Locus tag
    Dmel_CG4743
    See related
    AllianceGenome:FB:FBgn0039357
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4743; Samc
    Summary
    Predicted to enable S-adenosyl-L-methionine transmembrane transporter activity. Predicted to be involved in S-adenosyl-L-methionine transport. Predicted to be active in mitochondrial inner membrane. Used to study combined oxidative phosphorylation deficiency 28. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 28. Orthologous to human SLC25A26 (solute carrier family 25 member 26). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See CG4743 in Genome Data Viewer
    Location:
    96E9-96E9; 3-88 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25679242..25680550, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21504964..21506272, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Leucine-rich repeat-containing G protein-coupled receptor 3 Neighboring gene long non-coding RNA:CR45225 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma Neighboring gene Ribosomal protein L27 Neighboring gene Cardiolipin synthase

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables S-adenosyl-L-methionine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables S-adenosyl-L-methionine transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in S-adenosyl-L-methionine transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG4743-PA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25679242..25680550 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143158.2NP_651415.1  uncharacterized protein Dmel_CG4743 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651415.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4V4S1, Q9VBN7
      Related
      FBpp0084307
      Conserved Domains (2) summary
      PTZ00168
      Location:25281
      PTZ00168; mitochondrial carrier protein; Provisional
      pfam00153
      Location:199291
      Mito_carr; Mitochondrial carrier protein