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    CG34353 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 5740590, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG34353provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0085382
    Locus tag
    Dmel_CG34353
    See related
    AllianceGenome:FB:FBgn0085382
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12274; CG12427; CG12873; CG12874; CG12875; CG5566; CG5572; Dmel\CG34353
    Old locus tag
    CG12274; CG12427; CG12873; CG12874; CG12875; CG5566; CG5572; Dmel_CG12274; Dmel_CG12427; Dmel_CG12873; Dmel_CG12874; Dmel_CG12875; Dmel_CG5566; Dmel_CG5572
    Summary
    Predicted to enable axon guidance receptor activity. Involved in gravitaxis. Predicted to be active in axon; neuronal cell body; and plasma membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG34353 in Genome Data Viewer
    Location:
    98B2-98B5; 3-94 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (27767966..27905843, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (23593688..23731565, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ets at 98B Neighboring gene Odorant receptor 98a pseudogene Neighboring gene Odorant receptor 98a Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mitochondrial ribosomal protein S22 Neighboring gene Buddy of Hmr 1 Neighboring gene milkah

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A combinatorial code of transcription factors specifies subtypes of visual motion-sensing neurons in Drosophila. Hörmann N, et al. Development, 2020 May 13. PMID 32238425, Free PMC Article
    2. Genome-wide patterns of adaptation to temperate environments associated with transposable elements in Drosophila. González J, et al. PLoS Genet, 2010 Apr 8. PMID 20386746, Free PMC Article
    3. High rate of recent transposable element-induced adaptation in Drosophila melanogaster. González J, et al. PLoS Biol, 2008 Oct 21. PMID 18942889, Free PMC Article
    4. Multiple genetic loci affect place learning and memory performance in Drosophila melanogaster. Williams-Simon PA, et al. Genes Brain Behav, 2019 Sep. PMID 31095869, Free PMC Article
    5. Musashi expression in intestinal stem cells attenuates radiation-induced decline in intestinal permeability and survival in Drosophila. Sharma A, et al. Sci Rep, 2020 Nov 5. PMID 33154387, Free PMC Article

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c27858239-27856815 mobile_element_type = transposon:hopper{}1438
    • Loc: c27868256-27863009 mobile_element_type = transposon:Transpac{}1439

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables axon guidance receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in gravitaxis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synapse organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in axon IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in neuronal cell body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG34353-PA
    CG34353-PB
    CG34353-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      27767966..27905843 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001260413.1 → NP_001247342.1  uncharacterized protein Dmel_CG34353, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247342.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JPQ1, Q1RKQ9
      Conserved Domains (5) summary
      cd00096
      Location:290 → 359
      Ig; Immunoglobulin domain
      smart00408
      Location:198 → 258
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:191 → 269
      IG_like; Immunoglobulin like
      cd00063
      Location:466 → 524
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:273 → 360
      I-set; Immunoglobulin I-set domain

    2. NM_001300642.1 → NP_001287571.1  uncharacterized protein Dmel_CG34353, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287571.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LI09, Q1RKQ9
      Conserved Domains (5) summary
      cd00096
      Location:290 → 359
      Ig; Immunoglobulin domain
      smart00408
      Location:198 → 258
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:191 → 269
      IG_like; Immunoglobulin like
      cd00063
      Location:466 → 524
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:273 → 360
      I-set; Immunoglobulin I-set domain

    3. NM_001104479.2 → NP_001097949.1  uncharacterized protein Dmel_CG34353, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097949.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JPQ1, Q1RKQ9
      Conserved Domains (5) summary
      cd00096
      Location:290 → 359
      Ig; Immunoglobulin domain
      smart00408
      Location:198 → 258
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:191 → 269
      IG_like; Immunoglobulin like
      cd00063
      Location:466 → 524
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:273 → 360
      I-set; Immunoglobulin I-set domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LI09 A0A0B4LI09
    A8JPQ1 A8JPQ1

    Gene LinkOut

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