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    GRAMD4 GRAM domain containing 4 [ Bos taurus (domestic cattle) ]

    Gene ID: 613430, updated on 1-Jan-2025

    Summary

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    Official Symbol
    GRAMD4provided by VGNC
    Official Full Name
    GRAM domain containing 4provided by VGNC
    Primary source
    VGNC:VGNC:52784
    See related
    Ensembl:ENSBTAG00000021803
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    DIP
    Orthologs
    human mouse all
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    Genomic context

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    See GRAMD4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (116838171..116904409)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene tRNA mitochondrial 2-thiouridylase Neighboring gene cadherin EGF LAG seven-pass G-type receptor 1 Neighboring gene ceramide kinase Neighboring gene uncharacterized LOC101908206

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC165967

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of toll-like receptor 9 signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GRAM domain-containing protein 4
    Names
    death-inducing-protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102263.2 → NP_001095733.2  GRAM domain-containing protein 4

      Status: VALIDATED

      Source sequence(s)
      NKLS02000005
      UniProtKB/TrEMBL
      A0A3Q1M5T6
      Related
      ENSBTAP00000063639.2, ENSBTAT00000082593.2
      Conserved Domains (3) summary
      PTZ00121
      Location:122 → 227
      PTZ00121; MAEBL; Provisional
      cd13221
      Location:486 → 591
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam08372
      Location:331 → 411
      PRT_C; Plant phosphoribosyltransferase C-terminal

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      116838171..116904409
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059886669.1 → XP_059742652.1  GRAM domain-containing protein 4 isoform X1

      UniProtKB/TrEMBL
      F1MCP7
      Related
      ENSBTAP00000029061.6, ENSBTAT00000029061.6

    2. XM_005207531.5 → XP_005207588.1  GRAM domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_005207588.1

      UniProtKB/TrEMBL
      F1MCP7
      Conserved Domains (3) summary
      cd13221
      Location:460 → 565
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam08372
      Location:305 → 385
      PRT_C; Plant phosphoribosyltransferase C-terminal
      cl26511
      Location:96 → 201
      Neuromodulin_N; Gap junction protein N-terminal region

    3. XM_005207530.5 → XP_005207587.1  GRAM domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_005207587.1

      UniProtKB/TrEMBL
      F1MCP7
      Conserved Domains (3) summary
      cd13221
      Location:460 → 565
      PH-GRAM_GRAMDC4; GRAM domain-containing protein 4 (GRAMDC4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam08372
      Location:305 → 385
      PRT_C; Plant phosphoribosyltransferase C-terminal
      cl26511
      Location:96 → 201
      Neuromodulin_N; Gap junction protein N-terminal region
    Nucleotide Protein Strain
    Heading Accession and Version

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