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    FBXL20 F-box and leucine rich repeat protein 20 [ Bos taurus (domestic cattle) ]

    Gene ID: 511007, updated on 1-Jan-2025

    Summary

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    Official Symbol
    FBXL20provided by VGNC
    Official Full Name
    F-box and leucine rich repeat protein 20provided by VGNC
    Primary source
    VGNC:VGNC:52776
    See related
    BGD:BT16948; Ensembl:ENSBTAG00000008371
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    FBXL2
    Orthologs
    human mouse all
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    Genomic context

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    See FBXL20 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (39737410..39842818, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L19 Neighboring gene transcription factor CP2-like protein 1 Neighboring gene SH3 and cysteine rich domain 2 Neighboring gene large ribosomal subunit protein mL53 Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene mediator complex subunit 1 Neighboring gene microRNA mir-2342

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    F-box/LRR-repeat protein 20
    Names
    F-box and leucine-rich repeat protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001435015.1 → NP_001421944.1  F-box/LRR-repeat protein 20

      Status: VALIDATED

      Source sequence(s)
      NKLS02000019

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      39737410..39842818 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024979915.2 → XP_024835683.1  F-box/LRR-repeat protein 20 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M2Q0
      Conserved Domains (3) summary
      cd09293
      Location:222 → 396
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:121 → 146
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:30 → 71
      F-box-like

    2. XM_024979918.2 → XP_024835686.1  F-box/LRR-repeat protein 20 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1M2Q0
      Conserved Domains (3) summary
      cd09293
      Location:206 → 380
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:105 → 130
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:14 → 55
      F-box-like

    3. XM_024979919.2 → XP_024835687.1  F-box/LRR-repeat protein 20 isoform X4

      UniProtKB/TrEMBL
      A0AAA9T4K0
      Conserved Domains (2) summary
      cd09293
      Location:168 → 342
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:67 → 92
      LRR_AMN1; leucine-rich repeat [structural motif]

    RNA

    1. XR_003030626.2 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001035096.1: Suppressed sequence

      Description
      NM_001035096.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q58DG6.2 GenPept UniProtKB/Swiss-Prot:Q58DG6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.