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    CUL5 cullin 5 [ Bos taurus (domestic cattle) ]

    Gene ID: 510331, updated on 1-Jan-2025

    Summary

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    Official Symbol
    CUL5provided by VGNC
    Official Full Name
    cullin 5provided by VGNC
    Primary source
    VGNC:VGNC:27834
    See related
    BGD:BT26733; Ensembl:ENSBTAG00000012882
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CUL5 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (17591561..17721737)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 35 member F2 Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene RAB39A, member RAS oncogene family Neighboring gene U6 spliceosomal RNA Neighboring gene acetyl-CoA acetyltransferase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul5-RING ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of SCF ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cullin-5
    Names
    cullin-5-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      17591561..17721737
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005215787.4 → XP_005215844.1  cullin-5 isoform X3

      See identical proteins and their annotated locations for XP_005215844.1

      Conserved Domains (2) summary
      pfam00888
      Location:1 → 651
      Cullin; Cullin family
      pfam10557
      Location:690 → 750
      Cullin_Nedd8; Cullin protein neddylation domain

    2. XM_002692966.6 → XP_002693012.1  cullin-5 isoform X2

      See identical proteins and their annotated locations for XP_002693012.1

      UniProtKB/TrEMBL
      F1N7B5
      Related
      ENSBTAP00000053628.4, ENSBTAT00000061240.4
      Conserved Domains (2) summary
      pfam00888
      Location:19 → 672
      Cullin; Cullin family
      pfam10557
      Location:711 → 771
      Cullin_Nedd8; Cullin protein neddylation domain

    3. XM_024975725.2 → XP_024831493.1  cullin-5 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MXH0
      Related
      ENSBTAP00000060422.2, ENSBTAT00000068692.2
      Conserved Domains (2) summary
      pfam00888
      Location:36 → 687
      Cullin; Cullin family
      pfam10557
      Location:729 → 788
      Cullin_Nedd8; Cullin protein neddylation domain

    4. XM_059875074.1 → XP_059731057.1  cullin-5 isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version

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