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    HSPA4 heat shock protein family A (Hsp70) member 4 [ Bos taurus (domestic cattle) ]

    Gene ID: 536558, updated on 30-Jan-2025

    Summary

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    Official Symbol
    HSPA4provided by VGNC
    Official Full Name
    heat shock protein family A (Hsp70) member 4provided by VGNC
    Primary source
    VGNC:VGNC:52242
    See related
    BGD:BT11676; EnsemblRapid:ENSBTAG00070005903
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See HSPA4 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (44607161..44661126)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104969170 Neighboring gene large ribosomal subunit protein uL18-like Neighboring gene uncharacterized LOC132345747 Neighboring gene 5S ribosomal RNA Neighboring gene follistatin like 4 Neighboring gene uncharacterized LOC112447415

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP-dependent protein folding chaperone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    heat shock 70 kDa protein 4
    Names
    heat shock 70kDa protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001114192.2 → NP_001107664.1  heat shock 70 kDa protein 4

      See identical proteins and their annotated locations for NP_001107664.1

      Status: VALIDATED

      Source sequence(s)
      DV869849, DV882776, EE244161, EE365535, EE384978, EH134970, EH208217, NKLS02000007
      UniProtKB/TrEMBL
      A0AAA9TSF6, E1BBY7
      Related
      ENSBTAP00070007843.1, ENSBTAT00070013523.1
      Conserved Domains (2) summary
      cd11737
      Location:2 → 384
      HSPA4_NBD; Nucleotide-binding domain of HSPA4
      pfam00012
      Location:3 → 607
      HSP70; Hsp70 protein

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      44607161..44661126
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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