U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG34355 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42820, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG34355provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0085384
    Locus tag
    Dmel_CG34355
    See related
    AllianceGenome:FB:FBgn0085384
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12492; CG13818; Dmel\CG34355; lincRNA.840
    Old locus tag
    CG12492; Dmel_CG12492
    Summary
    Is expressed in adult head. Human ortholog(s) of this gene implicated in several diseases, including acute kidney failure; atypical hemolytic-uremic syndrome; cerebrovascular disease (multiple); rheumatoid arthritis; and thrombophilia (multiple). Orthologous to human THBD (thrombomodulin). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG34355 in Genome Data Viewer
    Location:
    95B8-95C5; 3-81 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23803859..23859167)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19629581..19676827)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Nucleoporin 98-96kD Neighboring gene myoblast city Neighboring gene uncharacterized protein Neighboring gene eukaryotic translation initiation factor 4G2 Neighboring gene long non-coding RNA:CR43285 Neighboring gene small nuclear RNA U1 at 95C c Neighboring gene small nuclear RNA U1 at 95C b Neighboring gene small nuclear RNA U1 at 95C a Neighboring gene Pellino

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. DOMON: an ancient extracellular domain in dopamine beta-monooxygenase and other proteins. Aravind L. Trends Biochem Sci, 2001 Sep. PMID 11551777
    2. Genetic control of cuticle formation during embryonic development of Drosophila melanogaster. Ostrowski S, et al. Genetics, 2002 May. PMID 12019232, Free PMC Article
    3. Duplicative and conservative transpositions of larval serum protein 1 genes in the genus Drosophila. González J, et al. Genetics, 2004 Sep. PMID 15454541, Free PMC Article
    4. Chronic low-dose γ-irradiation of Drosophila melanogaster larvae induces gene expression changes and enhances locomotive behavior. Kim CS, et al. J Radiat Res, 2015 May. PMID 25792464, Free PMC Article
    5. Highly constrained intergenic Drosophila ultraconserved elements are candidate ncRNAs. Kern AD, et al. Genome Biol Evol, 2015 Jan 23. PMID 25618141, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    mobile_element

    • Loc: 23835459-23844551 mobile_element_type = transposon:roo{}1411

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG34355-PB
    CG34355-PE
    CG34355-PF
    CG34355-PG

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      23803859..23859167
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300559.2 → NP_001287488.1  uncharacterized protein Dmel_CG34355, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287488.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VCG8
      Conserved Domains (3) summary
      smart00686
      Location:211 → 317
      DM13; Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis thaliana MBG8.9
      smart00664
      Location:343 → 508
      DoH; Possible catecholamine-binding domain present in a variety of eukaryotic proteins
      pfam10517
      Location:89 → 192
      DM13; Electron transfer DM13

    2. NM_001260340.3 → NP_001247269.1  uncharacterized protein Dmel_CG34355, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247269.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K709
      Conserved Domains (3) summary
      smart00686
      Location:211 → 317
      DM13; Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis thaliana MBG8.9
      smart00664
      Location:350 → 515
      DoH; Possible catecholamine-binding domain present in a variety of eukaryotic proteins
      pfam10517
      Location:89 → 192
      DM13; Electron transfer DM13

    3. NM_001104419.6 → NP_001097889.2  uncharacterized protein Dmel_CG34355, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097889.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VCG8
      Conserved Domains (3) summary
      smart00686
      Location:211 → 317
      DM13; Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis thaliana MBG8.9
      smart00664
      Location:343 → 508
      DoH; Possible catecholamine-binding domain present in a variety of eukaryotic proteins
      pfam10517
      Location:89 → 192
      DM13; Electron transfer DM13

    4. NM_001316615.1 → NP_001303544.1  uncharacterized protein Dmel_CG34355, isoform G [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A126GV09
      Conserved Domains (3) summary
      smart00686
      Location:210 → 316
      DM13; Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis thaliana MBG8.9
      smart00664
      Location:342 → 507
      DoH; Possible catecholamine-binding domain present in a variety of eukaryotic proteins
      pfam10517
      Location:88 → 191
      DM13; Electron transfer DM13
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4K709 A0A0B4K709
    A0A126GV09 A0A126GV09
    Q9VCG8 Q9VCG8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools