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    SYNRG synergin gamma [ Bos taurus (domestic cattle) ]

    Gene ID: 533098, updated on 27-Dec-2024

    Summary

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    Official Symbol
    SYNRGprovided by VGNC
    Official Full Name
    synergin gammaprovided by VGNC
    Primary source
    VGNC:VGNC:35533
    See related
    BGD:BT15043; Ensembl:ENSBTAG00000010292
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    AP1GBP1
    Orthologs
    human mouse all
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    Genomic context

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    See SYNRG in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (13810489..13895920, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene transcriptional adaptor 2A Neighboring gene uncharacterized LOC132343012 Neighboring gene dual specificity phosphatase 14 Neighboring gene DExD-box helicase 52 Neighboring gene HNF1 homeobox B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC157114

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of clathrin coat of trans-Golgi network vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    synergin gamma
    Names
    AP1 gamma subunit binding protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102152.2 → NP_001095622.1  synergin gamma

      See identical proteins and their annotated locations for NP_001095622.1

      Status: PROVISIONAL

      Source sequence(s)
      BC149473
      UniProtKB/TrEMBL
      A0A3Q1N3D4, A6QPT5
      Related
      ENSBTAP00000063966.2, ENSBTAT00000067614.2
      Conserved Domains (3) summary
      cd00052
      Location:385 → 435
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
      cl00928
      Location:115 → 149
      dsDNA_bind; Double-stranded DNA-binding domain
      cl09607
      Location:378 → 523
      Gly_reductase; Glycine/sarcosine/betaine reductase component B subunits

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      13810489..13895920 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005220017.5 → XP_005220074.1  synergin gamma isoform X6

      UniProtKB/TrEMBL
      A0AAA9U0I4
      Conserved Domains (3) summary
      cd00052
      Location:237 → 288
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
      cl00928
      Location:115 → 149
      dsDNA_bind; Double-stranded DNA-binding domain
      cl09607
      Location:230 → 375
      Gly_reductase; Glycine/sarcosine/betaine reductase component B subunits

    2. XM_005220018.5 → XP_005220075.1  synergin gamma isoform X7

      UniProtKB/TrEMBL
      A0A3Q1MYN7, A0AAA9U0I4
      Related
      ENSBTAP00000061200.2, ENSBTAT00000077558.2
      Conserved Domains (3) summary
      cd00052
      Location:238 → 289
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
      cl00928
      Location:116 → 150
      dsDNA_bind; Double-stranded DNA-binding domain
      cl09607
      Location:231 → 376
      Gly_reductase; Glycine/sarcosine/betaine reductase component B subunits

    3. XM_005220016.5 → XP_005220073.1  synergin gamma isoform X5

      UniProtKB/TrEMBL
      A0AAA9U0I4
      Conserved Domains (3) summary
      cd00052
      Location:238 → 289
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
      cl00928
      Location:116 → 150
      dsDNA_bind; Double-stranded DNA-binding domain
      cl09607
      Location:231 → 376
      Gly_reductase; Glycine/sarcosine/betaine reductase component B subunits

    4. XM_005220014.5 → XP_005220071.1  synergin gamma isoform X3

      UniProtKB/TrEMBL
      A0A3Q1MIN9
      Related
      ENSBTAP00000070601.2, ENSBTAT00000076983.2
      Conserved Domains (3) summary
      cd00052
      Location:316 → 367
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
      cl00928
      Location:116 → 150
      dsDNA_bind; Double-stranded DNA-binding domain
      cl09607
      Location:309 → 454
      Gly_reductase; Glycine/sarcosine/betaine reductase component B subunits

    5. XM_005220015.5 → XP_005220072.1  synergin gamma isoform X4

      UniProtKB/TrEMBL
      A0AAA9U0I4
      Related
      ENSBTAP00000102582.1, ENSBTAT00000123000.1
      Conserved Domains (3) summary
      cd00052
      Location:308 → 359
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
      cl00928
      Location:116 → 150
      dsDNA_bind; Double-stranded DNA-binding domain
      cl09607
      Location:301 → 446
      Gly_reductase; Glycine/sarcosine/betaine reductase component B subunits

    6. XM_015458543.3 → XP_015314029.1  synergin gamma isoform X9

      Conserved Domains (3) summary
      cd00052
      Location:386 → 437
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
      cl00928
      Location:116 → 150
      dsDNA_bind; Double-stranded DNA-binding domain
      cl09607
      Location:379 → 524
      Gly_reductase; Glycine/sarcosine/betaine reductase component B subunits

    7. XM_005220011.5 → XP_005220068.1  synergin gamma isoform X2

      UniProtKB/TrEMBL
      A0A3Q1N3D4, A0AAA9TQK4
      Related
      ENSBTAP00000100866.1, ENSBTAT00000128498.1
      Conserved Domains (3) summary
      cd00052
      Location:386 → 437
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
      cl00928
      Location:116 → 150
      dsDNA_bind; Double-stranded DNA-binding domain
      cl09607
      Location:379 → 524
      Gly_reductase; Glycine/sarcosine/betaine reductase component B subunits

    8. XM_005220010.5 → XP_005220067.1  synergin gamma isoform X1

      UniProtKB/TrEMBL
      A0A3Q1N3D4, F1MI41
      Related
      ENSBTAP00000013601.5, ENSBTAT00000013601.6
      Conserved Domains (3) summary
      cd00052
      Location:386 → 437
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
      cl00928
      Location:116 → 150
      dsDNA_bind; Double-stranded DNA-binding domain
      cl09607
      Location:379 → 524
      Gly_reductase; Glycine/sarcosine/betaine reductase component B subunits

    9. XM_010815774.4 → XP_010814076.1  synergin gamma isoform X8

      UniProtKB/TrEMBL
      A0A3Q1N3D4
      Conserved Domains (2) summary
      cd00052
      Location:202 → 253
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
      cl09607
      Location:195 → 340
      Gly_reductase; Glycine/sarcosine/betaine reductase component B subunits
    Nucleotide Protein Strain
    Heading Accession and Version

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