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    USP42 ubiquitin specific peptidase 42 [ Bos taurus (domestic cattle) ]

    Gene ID: 532721, updated on 1-Jan-2025

    Summary

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    Official Symbol
    USP42provided by VGNC
    Official Full Name
    ubiquitin specific peptidase 42provided by VGNC
    Primary source
    VGNC:VGNC:50065
    See related
    Ensembl:ENSBTAG00000000725
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See USP42 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (38074141..38130905)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene aminoacyl tRNA synthetase complex interacting multifunctional protein 2 Neighboring gene eukaryotic translation initiation factor 2 alpha kinase 1 Neighboring gene ankyrin repeat domain 61 Neighboring gene microRNA mir-12052 Neighboring gene cytohesin 3 Neighboring gene uncharacterized LOC132343907

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 42
    Names
    deubiquitinating enzyme 42
    ubiquitin thioesterase 42
    ubiquitin thiolesterase 42
    ubiquitin-specific-processing protease 42
    NP_001193568.1
    XP_024840745.1
    XP_059737353.1
    XP_059737354.1
    XP_059737355.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206639.1 → NP_001193568.1  ubiquitin carboxyl-terminal hydrolase 42

      See identical proteins and their annotated locations for NP_001193568.1

      Status: VALIDATED

      Source sequence(s)
      NKLS02000025
      UniProtKB/Swiss-Prot
      E1B9W9
      UniProtKB/TrEMBL
      A0AAA9TQ35
      Related
      ENSBTAP00000098489.1, ENSBTAT00000125227.1
      Conserved Domains (2) summary
      cd02661
      Location:110 → 410
      Peptidase_C19E; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cl26464
      Location:477 → 926
      Atrophin-1; Atrophin-1 family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      38074141..38130905
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059881371.1 → XP_059737354.1  ubiquitin carboxyl-terminal hydrolase 42 isoform X1

      UniProtKB/Swiss-Prot
      E1B9W9
      UniProtKB/TrEMBL
      A0AAA9TQ35

    2. XM_059881370.1 → XP_059737353.1  ubiquitin carboxyl-terminal hydrolase 42 isoform X1

      UniProtKB/Swiss-Prot
      E1B9W9
      UniProtKB/TrEMBL
      A0AAA9TQ35

    3. XM_024984977.2 → XP_024840745.1  ubiquitin carboxyl-terminal hydrolase 42 isoform X1

      UniProtKB/Swiss-Prot
      E1B9W9
      UniProtKB/TrEMBL
      A0AAA9TQ35
      Conserved Domains (2) summary
      cd02661
      Location:110 → 410
      Peptidase_C19E; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cl26464
      Location:477 → 926
      Atrophin-1; Atrophin-1 family

    4. XM_059881372.1 → XP_059737355.1  ubiquitin carboxyl-terminal hydrolase 42 isoform X1

      UniProtKB/Swiss-Prot
      E1B9W9
      UniProtKB/TrEMBL
      A0AAA9TQ35
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1B9W9.1 GenPept UniProtKB/Swiss-Prot:E1B9W9

    Gene LinkOut

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