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    Ir41a Ionotropic receptor 41a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 2768714, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ir41aprovided by FlyBase
    Official Full Name
    Ionotropic receptor 41aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040849
    Locus tag
    Dmel_CG33492
    See related
    AllianceGenome:FB:FBgn0040849
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    41a; CG17587; CG33492; DmelIR41a; Dmel\CG33492; IR41a
    Summary
    Predicted to enable ligand-gated monoatomic ion channel activity. Predicted to be involved in detection of chemical stimulus. Predicted to be located in membrane. Is expressed in adult olfactory receptor neuron Ir41a and antennal lobe glomerulus VM6. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ir41a in Genome Data Viewer
    Location:
    41C5-41D1; 2-55 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (4917519..5021955)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (805024..909460)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44105 Neighboring gene Troponin C at 41C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Neuropeptides Modulate Female Chemosensory Processing upon Mating in Drosophila. Hussain A, et al. PLoS Biol, 2016 May. PMID 27145127, Free PMC Article
    2. Lamin Dysfunction Mediates Neurodegeneration in Tauopathies. Frost B, et al. Curr Biol, 2016 Jan 11. PMID 26725200, Free PMC Article
    3. A dopamine-gated learning circuit underpins reproductive state-dependent odor preference in Drosophila females. Boehm AC, et al. Elife, 2022 Sep 21. PMID 36129174, Free PMC Article
    4. An ammonium transporter is a non-canonical olfactory receptor for ammonia. Vulpe A, et al. Curr Biol, 2021 Aug 9. PMID 34111404, Free PMC Article
    5. The Drosophila melanogaster phospholipid flippase dATP8B is required for odorant receptor function. Liu YC, et al. PLoS Genet, 2014 Mar. PMID 24651716, Free PMC Article

    See all (55) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. In the olfactory system IR41a mediates the long-range attraction to the odor.
      Title: Ionotropic Chemosensory Receptors Mediate the Taste and Smell of Polyamines.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    mobile_element

    • Loc: 4924184-4924237 mobile_element_type = transposon:pogo{}5970
    • Loc: 4924644-4929315 mobile_element_type = transposon:INE-1{}2831
    • Loc: 4924963-4929263 mobile_element_type = transposon:Doc{}590
    • Loc: 4930151-4930297 mobile_element_type = transposon:gypsy8{}1950
    • Loc: 4930675-4930757 mobile_element_type = transposon:G7{}2010
    • Loc: 4930773-4931964 mobile_element_type = transposon:G7{}2011
    • Loc: 4941604-4941866 mobile_element_type = transposon:1360{}6020
    • Loc: 4946105-4946137 mobile_element_type = transposon:accord2{}1993
    • Loc: 4959566-4959860 mobile_element_type = transposon:Cr1a{}595
    • Loc: 4969432-4969569 mobile_element_type = transposon:gypsy5{}2020
    • Loc: 4970876-4970982 mobile_element_type = transposon:INE-1{}5926
    • Loc: 4971726-4972551 mobile_element_type = transposon:Max{}6122
    • Loc: 4973309-4973581 mobile_element_type = transposon:HMS-Beagle{}5995
    • Loc: 4975303-4975622 mobile_element_type = transposon:INE-1{}5927
    • Loc: 4978836-4980793 mobile_element_type = transposon:gypsy12{}1911
    • Loc: 4981065-4981151 mobile_element_type = transposon:Rt1b{}599
    • Loc: 4981076-4983502 mobile_element_type = transposon:Doc3{}Ir41a[600]
    • Loc: 4982495-4983496 mobile_element_type = transposon:Rt1b{}601
    • Loc: 4983507-4985245 mobile_element_type = transposon:Rt1b{}602
    • Loc: 4985272-4986315 mobile_element_type = transposon:Rt1c{}603
    • Loc: 4986613-4986675 mobile_element_type = transposon:1360{}6022
    • Loc: 4995169-4995731 mobile_element_type = transposon:17.6{}1914
    • Loc: 4997335-4998500 mobile_element_type = transposon:gypsy8{}2842
    • Loc: 4999453-4999717 mobile_element_type = transposon:Max{}2844
    • Loc: 5002265-5002311 mobile_element_type = transposon:GATE{}6108
    • Loc: 5003233-5005102 mobile_element_type = transposon:Cr1a{}607
    • Loc: 5005199-5005384 mobile_element_type = transposon:INE-1{}5949
    • Loc: 5005393-5006078 mobile_element_type = transposon:Cr1a{}6062
    • Loc: 5007640-5008689 mobile_element_type = transposon:Max{}2845
    • Loc: 5014663-5016299 mobile_element_type = transposon:1360{}1624
    • Loc: 5018839-5019217 mobile_element_type = transposon:rooA{}1990

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 41a
    Names
    CG33492-PC
    Ir41a-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      4917519..5021955
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206022.4 → NP_995744.4  ionotropic receptor 41a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995744.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z6D6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z6D6 A1Z6D6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools