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    FUT8 fucosyltransferase 8 [ Bos taurus (domestic cattle) ]

    Gene ID: 281177, updated on 27-Dec-2024

    Summary

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    Official Symbol
    FUT8provided by VGNC
    Official Full Name
    fucosyltransferase 8provided by VGNC
    Primary source
    VGNC:VGNC:29152
    See related
    BGD:BT15852; Ensembl:ENSBTAG00000019819
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See FUT8 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (77507902..77838156)

    Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132346397 Neighboring gene U6 spliceosomal RNA Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene uncharacterized LOC132346398 Neighboring gene uncharacterized LOC104973214

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Ancestral exonic organization of FUT8, the gene encoding the alpha6-fucosyltransferase, reveals successive peptide domains which suggest a particular three-dimensional core structure for the alpha6-fucosyltransferase family. Javaud C, et al. Mol Biol Evol, 2000 Nov. PMID 11070054
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC129067

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glycoprotein 6-alpha-L-fucosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in N-glycan fucosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein N-linked glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi cisterna membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha-(1,6)-fucosyltransferase
    Names
    GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase
    GDP-fucose--glycoprotein fucosyltransferase
    alpha1-6FucT
    fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
    glycoprotein 6-alpha-L-fucosyltransferase
    NP_803467.2
    XP_005211979.1
    XP_005211980.1
    XP_010807742.1
    XP_024852998.1
    XP_024852999.1
    XP_024853000.1
    XP_024853003.1
    XP_024853004.1
    XP_059746171.1
    XP_059746173.1
    XP_059746174.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177501.2 → NP_803467.2  alpha-(1,6)-fucosyltransferase

      See identical proteins and their annotated locations for NP_803467.2

      Status: PROVISIONAL

      Source sequence(s)
      BC104555
      UniProtKB/Swiss-Prot
      Q9N0W2
      UniProtKB/TrEMBL
      Q3SX18
      Related
      ENSBTAP00000026406.6, ENSBTAT00000026406.7
      Conserved Domains (3) summary
      cd11300
      Location:174 → 499
      Fut8_like; Alpha 1-6-fucosyltransferase
      cd11792
      Location:506 → 560
      SH3_Fut8; Src homology 3 domain of Alpha1,6-fucosyltransferase (Fut8)
      pfam02050
      Location:41 → 151
      FliJ; Flagellar FliJ protein

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      77507902..77838156
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024997231.2 → XP_024852999.1  alpha-(1,6)-fucosyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q9N0W2
      Conserved Domains (3) summary
      cd11300
      Location:174 → 499
      Fut8_like; Alpha 1-6-fucosyltransferase
      cd11792
      Location:506 → 560
      SH3_Fut8; Src homology 3 domain of Alpha1,6-fucosyltransferase (Fut8)
      cl26819
      Location:50 → 157
      tRNA_SAD; Threonyl and Alanyl tRNA synthetase second additional domain

    2. XM_005211923.5 → XP_005211980.1  alpha-(1,6)-fucosyltransferase isoform X1

      See identical proteins and their annotated locations for XP_005211980.1

      UniProtKB/Swiss-Prot
      Q9N0W2
      Conserved Domains (3) summary
      cd11300
      Location:174 → 499
      Fut8_like; Alpha 1-6-fucosyltransferase
      cd11792
      Location:506 → 560
      SH3_Fut8; Src homology 3 domain of Alpha1,6-fucosyltransferase (Fut8)
      cl26819
      Location:50 → 157
      tRNA_SAD; Threonyl and Alanyl tRNA synthetase second additional domain

    3. XM_024997235.2 → XP_024853003.1  alpha-(1,6)-fucosyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q9N0W2
      Conserved Domains (3) summary
      cd11300
      Location:174 → 499
      Fut8_like; Alpha 1-6-fucosyltransferase
      cd11792
      Location:506 → 560
      SH3_Fut8; Src homology 3 domain of Alpha1,6-fucosyltransferase (Fut8)
      cl26819
      Location:50 → 157
      tRNA_SAD; Threonyl and Alanyl tRNA synthetase second additional domain

    4. XM_059890188.1 → XP_059746171.1  alpha-(1,6)-fucosyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q9N0W2

    5. XM_024997230.2 → XP_024852998.1  alpha-(1,6)-fucosyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q9N0W2
      Conserved Domains (3) summary
      cd11300
      Location:174 → 499
      Fut8_like; Alpha 1-6-fucosyltransferase
      cd11792
      Location:506 → 560
      SH3_Fut8; Src homology 3 domain of Alpha1,6-fucosyltransferase (Fut8)
      cl26819
      Location:50 → 157
      tRNA_SAD; Threonyl and Alanyl tRNA synthetase second additional domain

    6. XM_024997232.2 → XP_024853000.1  alpha-(1,6)-fucosyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q9N0W2
      Conserved Domains (3) summary
      cd11300
      Location:174 → 499
      Fut8_like; Alpha 1-6-fucosyltransferase
      cd11792
      Location:506 → 560
      SH3_Fut8; Src homology 3 domain of Alpha1,6-fucosyltransferase (Fut8)
      cl26819
      Location:50 → 157
      tRNA_SAD; Threonyl and Alanyl tRNA synthetase second additional domain

    7. XM_010809440.4 → XP_010807742.1  alpha-(1,6)-fucosyltransferase isoform X1

      See identical proteins and their annotated locations for XP_010807742.1

      UniProtKB/Swiss-Prot
      Q9N0W2
      Conserved Domains (3) summary
      cd11300
      Location:174 → 499
      Fut8_like; Alpha 1-6-fucosyltransferase
      cd11792
      Location:506 → 560
      SH3_Fut8; Src homology 3 domain of Alpha1,6-fucosyltransferase (Fut8)
      cl26819
      Location:50 → 157
      tRNA_SAD; Threonyl and Alanyl tRNA synthetase second additional domain

    8. XM_005211922.5 → XP_005211979.1  alpha-(1,6)-fucosyltransferase isoform X1

      See identical proteins and their annotated locations for XP_005211979.1

      UniProtKB/Swiss-Prot
      Q9N0W2
      Conserved Domains (3) summary
      cd11300
      Location:174 → 499
      Fut8_like; Alpha 1-6-fucosyltransferase
      cd11792
      Location:506 → 560
      SH3_Fut8; Src homology 3 domain of Alpha1,6-fucosyltransferase (Fut8)
      cl26819
      Location:50 → 157
      tRNA_SAD; Threonyl and Alanyl tRNA synthetase second additional domain

    9. XM_024997236.2 → XP_024853004.1  alpha-(1,6)-fucosyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q9N0W2
      Conserved Domains (3) summary
      cd11300
      Location:174 → 499
      Fut8_like; Alpha 1-6-fucosyltransferase
      cd11792
      Location:506 → 560
      SH3_Fut8; Src homology 3 domain of Alpha1,6-fucosyltransferase (Fut8)
      cl26819
      Location:50 → 157
      tRNA_SAD; Threonyl and Alanyl tRNA synthetase second additional domain

    10. XM_059890190.1 → XP_059746173.1  alpha-(1,6)-fucosyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q9N0W2

    11. XM_059890191.1 → XP_059746174.1  alpha-(1,6)-fucosyltransferase isoform X1

      UniProtKB/Swiss-Prot
      Q9N0W2
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9N0W2.1 GenPept UniProtKB/Swiss-Prot:Q9N0W2

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