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    UNC45B unc-45 myosin chaperone B [ Bos taurus (domestic cattle) ]

    Gene ID: 535385, updated on 1-Jan-2025

    Summary

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    Official Symbol
    UNC45Bprovided by VGNC
    Official Full Name
    unc-45 myosin chaperone Bprovided by VGNC
    Primary source
    VGNC:VGNC:36668
    See related
    BGD:BT25990; Ensembl:ENSBTAG00000002898
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See UNC45B in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (14914284..14947266, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene schlafen family member 5-like Neighboring gene U7 small nuclear RNA Neighboring gene notchless homolog 1 Neighboring gene fibronectin type III domain containing 8

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables Hsp90 protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chaperone-mediated protein folding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein unc-45 homolog B
    Names
    unc-45 homolog B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      14914284..14947266 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002695630.6 → XP_002695676.1  protein unc-45 homolog B

      See identical proteins and their annotated locations for XP_002695676.1

      UniProtKB/TrEMBL
      F1MFZ5
      Related
      ENSBTAP00000003766.6, ENSBTAT00000003766.6
      Conserved Domains (5) summary
      cd00020
      Location:716 → 831
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      sd00006
      Location:6 → 34
      TPR; TPR repeat [structural motif]
      pfam11701
      Location:344 → 489
      UNC45-central; Myosin-binding striated muscle assembly central
      pfam13414
      Location:5 → 73
      TPR_11; TPR repeat
      sd00043
      Location:752 → 786
      ARM; armadillo repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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