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    GGT1 gamma-glutamyltransferase 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 615582, updated on 30-Jan-2025

    Summary

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    Gene symbol
    GGT1
    Gene description
    gamma-glutamyltransferase 1
    See related
    BGD:BT17441; EnsemblRapid:ENSBTAG00070024023
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See GGT1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (71455671..71471669, complement)

    Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132342661 Neighboring gene sushi domain containing 2 Neighboring gene gamma-glutamyltransferase 5 Neighboring gene transfer RNA glutamine (anticodon UUG) Neighboring gene small nuclear ribonucleoprotein D3 polypeptide

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Glutathione content and expression of proteins involved with glutathione metabolism differs in longissimus dorsi, subcutaneous adipose, and liver tissues of finished vs. growing beef steers. Huang J, et al. J Anim Sci, 2018 Dec 3. PMID 30204884, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutathione hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutathione catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptide modification IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of immune system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutathione hydrolase 1 proenzyme
    NP_001193143.2
    XP_024833224.1
    XP_024833225.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206214.2 → NP_001193143.2  glutathione hydrolase 1 proenzyme

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000017
      UniProtKB/TrEMBL
      G3N2D8
      Related
      ENSBTAP00070032406.1, ENSBTAT00070054052.1
      Conserved Domains (1) summary
      pfam01019
      Location:55 → 563
      G_glu_transpept; Gamma-glutamyltranspeptidase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      71455671..71471669 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024977457.2 → XP_024833225.1  glutathione hydrolase 1 proenzyme isoform X1

      UniProtKB/TrEMBL
      G3N2D8
      Conserved Domains (1) summary
      pfam01019
      Location:55 → 563
      G_glu_transpept; Gamma-glutamyltranspeptidase

    2. XM_024977456.2 → XP_024833224.1  glutathione hydrolase 1 proenzyme isoform X1

      UniProtKB/TrEMBL
      G3N2D8
      Conserved Domains (1) summary
      pfam01019
      Location:55 → 563
      G_glu_transpept; Gamma-glutamyltranspeptidase
    Nucleotide Protein Strain
    Heading Accession and Version

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