U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    DOCK11 dedicator of cytokinesis 11 [ Bos taurus (domestic cattle) ]

    Gene ID: 537297, updated on 29-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    DOCK11provided by VGNC
    Official Full Name
    dedicator of cytokinesis 11provided by VGNC
    Primary source
    VGNC:VGNC:28156
    See related
    BGD:BT25528; Ensembl:ENSBTAG00000006439
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See DOCK11 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    58
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (2680473..3007250)

    Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104970458 Neighboring gene WD repeat domain 44 Neighboring gene microRNA mir-1277 Neighboring gene microRNA mir-2284w Neighboring gene uncharacterized LOC112445050 Neighboring gene dedicator of cytokinesis protein 11-like

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC140073

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in marginal zone B cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of filopodium assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    dedicator of cytokinesis protein 11

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076090.3 → NP_001069558.3  dedicator of cytokinesis protein 11

      Status: VALIDATED

      Source sequence(s)
      DAAA02067106, DAAA02067108, DAAA02067109
      UniProtKB/TrEMBL
      G5E580
      Conserved Domains (5) summary
      cd08697
      Location:639 → 828
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11700
      Location:1615 → 2027
      DHR2_DOCK11; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 11
      cd13267
      Location:161 → 284
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam00169
      Location:166 → 271
      PH; PH domain
      pfam11878
      Location:54 → 145
      DUF3398; Domain of unknown function (DUF3398)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      2680473..3007250
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024988142.2 → XP_024843910.1  dedicator of cytokinesis protein 11 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SFY1, G5E580
      Related
      ENSBTAP00070033859.1, ENSBTAT00070056588.1
      Conserved Domains (4) summary
      cd08697
      Location:639 → 828
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11700
      Location:1628 → 2040
      DHR2_DOCK11; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 11
      cd13267
      Location:161 → 284
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:54 → 145
      DUF3398; Domain of unknown function (DUF3398)

    2. XM_024988144.2 → XP_024843912.1  dedicator of cytokinesis protein 11 isoform X3

      UniProtKB/TrEMBL
      A0AAA9RWR6
      Conserved Domains (4) summary
      cd08697
      Location:639 → 828
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd13267
      Location:161 → 284
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:54 → 145
      DUF3398; Domain of unknown function (DUF3398)
      cl06123
      Location:1628 → 2002
      DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

    3. XM_024988146.2 → XP_024843914.1  dedicator of cytokinesis protein 11 isoform X5

      UniProtKB/TrEMBL
      A0AAA9SJD9
      Conserved Domains (4) summary
      cd08697
      Location:639 → 828
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd13267
      Location:161 → 284
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:54 → 145
      DUF3398; Domain of unknown function (DUF3398)
      cl06123
      Location:1382 → 1765
      DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

    4. XM_024988143.2 → XP_024843911.1  dedicator of cytokinesis protein 11 isoform X2

      UniProtKB/TrEMBL
      A0AAA9TMC1, G5E580
      Conserved Domains (4) summary
      cd08697
      Location:639 → 828
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11700
      Location:1615 → 2027
      DHR2_DOCK11; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 11
      cd13267
      Location:161 → 284
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:54 → 145
      DUF3398; Domain of unknown function (DUF3398)

    5. XM_024988145.2 → XP_024843913.1  dedicator of cytokinesis protein 11 isoform X4

      UniProtKB/TrEMBL
      G5E580
      Related
      ENSBTAP00070033872.1, ENSBTAT00070056618.1
      Conserved Domains (4) summary
      cd08697
      Location:639 → 828
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11700
      Location:1628 → 2040
      DHR2_DOCK11; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 11
      cd13267
      Location:161 → 284
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:54 → 145
      DUF3398; Domain of unknown function (DUF3398)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.