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    CG6790 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41388, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6790provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037915
    Locus tag
    Dmel_CG6790
    See related
    AllianceGenome:FB:FBgn0037915
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.186; Dmel\CG6790; NEST:bs22e02
    Summary
    Predicted to enable mannose-ethanolamine phosphotransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in multiple congenital anomalies-hypotonia-seizures syndrome 1. Orthologous to human PIGN (phosphatidylinositol glycan anchor biosynthesis class N). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6790 in Genome Data Viewer
    Location:
    86E11-86E11; 3-51 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11575901..11578745, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7401623..7404467, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene fatty acid binding protein Neighboring gene scheggia Neighboring gene Multidrug resistance protein 4 Neighboring gene uncharacterized protein Neighboring gene whacked

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila dMRP4 regulates responsiveness to O2 deprivation and development under hypoxia. Huang H, et al. Physiol Genomics, 2007 May 11. PMID 17284667
    2. Jupiter, a new Drosophila protein associated with microtubules. Karpova N, et al. Cell Motil Cytoskeleton, 2006 May. PMID 16518797
    3. The KH-type RNA-binding protein PSI is required for Drosophila viability, male fertility, and cellular mRNA processing. Labourier E, et al. Genes Dev, 2002 Jan 1. PMID 11782446, Free PMC Article
    4. Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway. Dimova DK, et al. Genes Dev, 2003 Sep 15. PMID 12975318, Free PMC Article
    5. Quantitative proteomics and phosphoproteomics reveal insights into mechanisms of ocnus function in Drosophila testis development. Zheng Y, et al. BMC Genomics, 2023 May 26. PMID 37237333, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables mannose-ethanolamine phosphotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mannose-ethanolamine phosphotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in GPI anchor biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in GPI anchor biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6790-PA
    NP_650087.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      11575901..11578745 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141830.3 → NP_650087.2  uncharacterized protein Dmel_CG6790 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650087.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VGM0, V5NZV7
      Related
      FBpp0081936
      Conserved Domains (2) summary
      pfam04987
      Location:418 → 821
      PigN; Phosphatidylinositolglycan class N (PIG-N)
      cd16020
      Location:83 → 331
      GPI_EPT_1; GPI ethanolamine phosphate transferase 1; PIG-N
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K2X3 Q7K2X3
    Q9VGM0 Q9VGM0

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