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    MRPL18 mitochondrial ribosomal protein L18 [ Bos taurus (domestic cattle) ]

    Gene ID: 534352, updated on 30-Jan-2025

    Summary

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    Official Symbol
    MRPL18provided by VGNC
    Official Full Name
    mitochondrial ribosomal protein L18provided by VGNC
    Primary source
    VGNC:VGNC:31621
    See related
    BGD:BT20584; EnsemblRapid:ENSBTAG00070034452
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See MRPL18 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 9 NC_037336.1 (96056503..96061781)

    Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene acetyl-CoA acetyltransferase 2 Neighboring gene small nucleolar RNA SNORA20 Neighboring gene small nucleolar RNA SNORA29 Neighboring gene t-complex 1 Neighboring gene PARN like ribonuclease domain containing exonuclease 1 Neighboring gene MAS1 proto-oncogene, G protein-coupled receptor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037336.1 Chromosome 9 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC128595

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 5S rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    large ribosomal subunit protein uL18m
    Names
    39S ribosomal protein L18, mitochondrial
    L18mt
    MRP-L18

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034608.2 → NP_001029780.1  large ribosomal subunit protein uL18m

      See identical proteins and their annotated locations for NP_001029780.1

      Status: PROVISIONAL

      Source sequence(s)
      BC103149
      UniProtKB/Swiss-Prot
      Q3ZBR7
      UniProtKB/TrEMBL
      A0AAF6YI06
      Related
      ENSBTAP00070047235.1, ENSBTAT00070077462.1
      Conserved Domains (1) summary
      cd00432
      Location:68 → 170
      Ribosomal_L18_L5e; Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037336.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      96056503..96061781
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015472928.3 → XP_015328414.1  large ribosomal subunit protein uL18m isoform X1

      Conserved Domains (1) summary
      cd00432
      Location:68 → 109
      Ribosomal_L18_L5e; Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3ZBR7.1 GenPept UniProtKB/Swiss-Prot:Q3ZBR7

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