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    MAP1LC3B microtubule associated protein 1 light chain 3 beta [ Bos taurus (domestic cattle) ]

    Gene ID: 408001, updated on 1-Jan-2025

    Summary

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    Gene symbol
    MAP1LC3B
    Gene description
    microtubule associated protein 1 light chain 3 beta
    See related
    BGD:BT25974; Ensembl:ENSBTAG00000011632
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See MAP1LC3B in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (12973367..12986925)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene F-box protein 31 Neighboring gene uncharacterized LOC100848507 Neighboring gene zinc finger CCHC-type containing 14 Neighboring gene junctophilin 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Insertion of a sequence encoding light chain 3 of microtubule-associated proteins 1A and 1B in a pestivirus genome: connection with virus cytopathogenicity and induction of lethal disease in cattle. Meyers G, et al. J Virol, 1998 May. PMID 9557703, Free PMC Article
    2. Processing of a pestivirus protein by a cellular protease specific for light chain 3 of microtubule-associated proteins. Fricke J, et al. J Virol, 2004 Jun. PMID 15140988, Free PMC Article
    3. Molecular characterization of light chain 3. A microtubule binding subunit of MAP1A and MAP1B. Mann SS, et al. J Biol Chem, 1994 Apr 15. PMID 7908909
    4. LC3 conjugation system in mammalian autophagy. Tanida I, et al. Int J Biochem Cell Biol, 2004 Dec. PMID 15325588, Free PMC Article
    5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in autophagosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in autophagosome maturation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in autophagy of mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to nitrogen starvation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in macroautophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in autophagosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in autophagosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    microtubule-associated proteins 1A/1B light chain 3B
    Names
    MAP1 light chain 3-like protein 2
    MAP1A/1B light chain 3 B
    MAP1A/MAP1B LC3 B
    MAP1A/MAP1B light chain 3 B
    autophagy-related protein LC3 B
    autophagy-related ubiquitin-like modifier LC3 B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001169.1 → NP_001001169.1  microtubule-associated proteins 1A/1B light chain 3B

      See identical proteins and their annotated locations for NP_001001169.1

      Status: PROVISIONAL

      Source sequence(s)
      AY570553
      UniProtKB/Swiss-Prot
      O41515, Q6PZ01
      UniProtKB/TrEMBL
      A0AAA9TDA5
      Related
      ENSBTAP00000015449.5, ENSBTAT00000015449.6
      Conserved Domains (1) summary
      cd17235
      Location:5 → 119
      Ubl_ATG8_MAP1LC3B; ubiquitin-like (Ubl) domain found in microtubule associate protein 1 light chain 3B (MAP1LC3B)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      12973367..12986925
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024977975.2 → XP_024833743.1  microtubule-associated proteins 1A/1B light chain 3B isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O41515.4 GenPept UniProtKB/Swiss-Prot:O41515

    Gene LinkOut

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