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    TREX1 three prime repair exonuclease 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 282099, updated on 27-Dec-2024

    Summary

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    Official Symbol
    TREX1provided by VGNC
    Official Full Name
    three prime repair exonuclease 1provided by VGNC
    Primary source
    VGNC:VGNC:36303
    See related
    BGD:BT10908
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See TREX1 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (51399388..51401262, complement)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 Neighboring gene shisa family member 5 Neighboring gene ATR interacting protein Neighboring gene coiled-coil domain containing 51 Neighboring gene translation machinery associated 7 homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Structure and expression of the TREX1 and TREX2 3' --> 5' exonuclease genes. Mazur DJ, et al. J Biol Chem, 2001 May 4. PMID 11278605
    2. Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases. Mazur DJ, et al. J Biol Chem, 1999 Jul 9. PMID 10391904
    3. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    4. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3'-5'-DNA exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    three-prime repair exonuclease 1
    Names
    3'-5' exonuclease TREX1
    NP_776900.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174475.3 → NP_776900.2  three-prime repair exonuclease 1

      See identical proteins and their annotated locations for NP_776900.2

      Status: PROVISIONAL

      Source sequence(s)
      BT020893
      UniProtKB/TrEMBL
      F6QB70, Q5E9M7
      Conserved Domains (1) summary
      cd06136
      Location:14 → 211
      TREX1_2; DEDDh 3'-5' exonuclease domain of three prime repair exonuclease (TREX)1, TREX2, and similar proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      51399388..51401262 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9BG99.1 GenPept UniProtKB/Swiss-Prot:Q9BG99

    Gene LinkOut

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    Research Materials