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    SRPX2 sushi repeat containing protein X-linked 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 514742, updated on 30-Jan-2025

    Summary

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    Gene symbol
    SRPX2
    Gene description
    sushi repeat containing protein X-linked 2
    See related
    BGD:BT16440; EnsemblRapid:ENSBTAG00070025702
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SRPX2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (49648129..49677923)

    Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene tenomodulin Neighboring gene tetraspanin 6 Neighboring gene E3 ubiquitin-protein ligase RNF168-like Neighboring gene brain expressed X-linked 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell migration involved in sprouting angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of synapse assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sushi repeat-containing protein SRPX2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014926.1 → NP_001014926.1  sushi repeat-containing protein SRPX2 precursor

      See identical proteins and their annotated locations for NP_001014926.1

      Status: PROVISIONAL

      Source sequence(s)
      BT020744
      UniProtKB/Swiss-Prot
      Q5EA25
      UniProtKB/TrEMBL
      A0AAA9TPA0
      Related
      ENSBTAP00070034654.1, ENSBTAT00070058235.1
      Conserved Domains (3) summary
      cd00033
      Location:264 → 320
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      pfam02494
      Location:177 → 259
      HYR; HYR domain
      pfam13778
      Location:334 → 445
      DUF4174; Domain of unknown function (DUF4174)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      49648129..49677923
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010821633.4 → XP_010819935.1  sushi repeat-containing protein SRPX2 isoform X2

      See identical proteins and their annotated locations for XP_010819935.1

      UniProtKB/TrEMBL
      A0AAF6DMC1
      Conserved Domains (3) summary
      cd00033
      Location:264 → 320
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      pfam02494
      Location:177 → 259
      HYR; HYR domain
      pfam13778
      Location:334 → 366
      DUF4174; Domain of unknown function (DUF4174)

    2. XM_059883377.1 → XP_059739360.1  sushi repeat-containing protein SRPX2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TPA0, A6H7A3, F1MK26
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5EA25.1 GenPept UniProtKB/Swiss-Prot:Q5EA25

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