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    MTUS1 microtubule associated scaffold protein 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 515016, updated on 1-Jan-2025

    Summary

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    Official Symbol
    MTUS1provided by VGNC
    Official Full Name
    microtubule associated scaffold protein 1provided by VGNC
    Primary source
    VGNC:VGNC:31756
    See related
    BGD:BT26744; Ensembl:ENSBTAG00000039682
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See MTUS1 in Genome Data Viewer
    Location:
    chromosome: 27
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 27 NC_037354.1 (19445839..19632316)

    Chromosome 27 - NC_037354.1Genomic Context describing neighboring genes Neighboring gene pericentriolar material 1 Neighboring gene microRNA mir-2398 Neighboring gene fibrinogen like 1 Neighboring gene microRNA mir-2284ac Neighboring gene uncharacterized LOC112444680 Neighboring gene U6atac minor spliceosomal RNA Neighboring gene platelet derived growth factor receptor like Neighboring gene uncharacterized LOC104976061

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037354.1 Chromosome 27 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC157363

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of macrophage chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    microtubule-associated tumor suppressor 1 homolog
    Names
    microtubule associated tumor suppressor 1
    mitochondrial tumor suppressor 1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075692.2 → NP_001069160.1  microtubule-associated tumor suppressor 1 homolog isoform 2

      See identical proteins and their annotated locations for NP_001069160.1

      Status: VALIDATED

      Source sequence(s)
      BC118198
      UniProtKB/Swiss-Prot
      Q17QT2
      UniProtKB/TrEMBL
      A0AAA9T975
      Related
      ENSBTAP00000002556.3, ENSBTAT00000002556.5
      Conserved Domains (1) summary
      TIGR02168
      Location:85 → 385
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    2. NM_001372083.1 → NP_001359012.1  microtubule-associated tumor suppressor 1 homolog isoform 1

      Status: VALIDATED

      Source sequence(s)
      NKLS02000027
      UniProtKB/TrEMBL
      A0AAA9T6G2, A0AAA9T975
      Related
      ENSBTAP00000093473.1, ENSBTAT00000096686.1
      Conserved Domains (1) summary
      TIGR02168
      Location:166 → 466
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037354.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      19445839..19632316
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059882221.1 → XP_059738204.1  microtubule-associated tumor suppressor 1 homolog isoform X1

      UniProtKB/TrEMBL
      A0AAA9RWR0, A0AAA9U2R3
      Related
      ENSBTAP00000103936.1, ENSBTAT00000109706.1

    2. XM_015460846.3 → XP_015316332.1  microtubule-associated tumor suppressor 1 homolog isoform X1

      UniProtKB/TrEMBL
      A0AAA9RWR0, A0AAA9U2R3
      Conserved Domains (2) summary
      pfam09755
      Location:952 → 1237
      DUF2046; Uncharacterized conserved protein H4 (DUF2046)
      cl23720
      Location:1064 → 1188
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    3. XM_005225980.5 → XP_005226037.1  microtubule-associated tumor suppressor 1 homolog isoform X1

      UniProtKB/TrEMBL
      A0AAA9RWR0, A0AAA9U2R3
      Related
      ENSBTAP00000077883.1, ENSBTAT00000092650.1
      Conserved Domains (2) summary
      pfam09755
      Location:952 → 1237
      DUF2046; Uncharacterized conserved protein H4 (DUF2046)
      cl23720
      Location:1064 → 1188
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    4. XM_010820259.4 → XP_010818561.1  microtubule-associated tumor suppressor 1 homolog isoform X3

      UniProtKB/TrEMBL
      A0AAA9RWR0, A0AAA9SZ01
      Related
      ENSBTAP00000089313.1, ENSBTAT00000112529.1
      Conserved Domains (3) summary
      pfam12718
      Location:962 → 1108
      Tropomyosin_1; Tropomyosin like
      pfam13851
      Location:887 → 1019
      GAS; Growth-arrest specific micro-tubule binding
      cl23720
      Location:970 → 1094
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    5. XM_010820258.4 → XP_010818560.1  microtubule-associated tumor suppressor 1 homolog isoform X2

      UniProtKB/TrEMBL
      A0AAA9RWR0, A0AAA9T8L0
      Related
      ENSBTAP00000092210.1, ENSBTAT00000103482.1
      Conserved Domains (2) summary
      pfam09755
      Location:898 → 1183
      DUF2046; Uncharacterized conserved protein H4 (DUF2046)
      cl23720
      Location:1010 → 1134
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    6. XM_059882222.1 → XP_059738205.1  microtubule-associated tumor suppressor 1 homolog isoform X4

      UniProtKB/TrEMBL
      A0AAA9T975

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001190425.1: Suppressed sequence

      Description
      NM_001190425.1: This RefSeq was temporarily suppressed because the CDS was partial.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q17QT2.1 GenPept UniProtKB/Swiss-Prot:Q17QT2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials