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    NaPi-III Na[+]-dependent inorganic phosphate cotransporter type III [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39255, updated on 9-Dec-2024

    Summary

    Official Symbol
    NaPi-IIIprovided by FlyBase
    Official Full Name
    Na[+]-dependent inorganic phosphate cotransporter type IIIprovided by FlyBase
    Primary source
    FLYBASE:FBgn0260795
    Locus tag
    Dmel_CG42575
    See related
    AllianceGenome:FB:FBgn0260795
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG42575; CG7628; CR32078; Dmel\CG42575; dPit; dPiT; Dromel_CG7628_FBtr0076213_mORF
    Old locus tag
    Dmel_CG7628; Dmel_CR32078
    Summary
    Enables sodium:phosphate symporter activity. Involved in sodium-dependent phosphate transport. Predicted to be located in membrane. Is expressed in several structures, including adult head; central brain primordium; ganglia; larval nervous system; and mesoderm. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human SLC20A1 (solute carrier family 20 member 1) and SLC20A2 (solute carrier family 20 member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See NaPi-III in Genome Data Viewer
    Location:
    68A7-68A8; 3-34 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11123348..11134663)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11116448..11127763)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Forkhead box K Neighboring gene mitochondrial ribosomal protein L2 Neighboring gene Ubiquitin fusion-degradation 1-like Neighboring gene uncharacterized protein Neighboring gene no optic lobe Neighboring gene uncharacterized protein Neighboring gene Insulin receptor substrate 53 kDa Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables sodium:phosphate symporter activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in phosphate ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in phosphate ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sodium-dependent phosphate transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Na[+]-dependent inorganic phosphate cotransporter type III
    Names
    CG42575-PA
    CG42575-PB
    CR32078
    NaPi-III-PA
    NaPi-III-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      11123348..11134663
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140184.4NP_648441.1  Na[+]-dependent inorganic phosphate cotransporter type III, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648441.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZT3, Q9VTG0
      Related
      FBpp0290653
      Conserved Domains (2) summary
      COG0306
      Location:8227
      PitA; Phosphate/sulfate permease [Inorganic ion transport and metabolism]
      pfam01384
      Location:29151
      PHO4; Phosphate transporter family
    2. NM_001274775.1NP_001261704.1  Na[+]-dependent inorganic phosphate cotransporter type III, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261704.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZT3, Q9VTG0
      Conserved Domains (2) summary
      COG0306
      Location:8227
      PitA; Phosphate/sulfate permease [Inorganic ion transport and metabolism]
      pfam01384
      Location:29151
      PHO4; Phosphate transporter family