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    Ldaf1 Lipid droplet assembly factor 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 326240, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ldaf1provided by FlyBase
    Official Full Name
    Lipid droplet assembly factor 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0052803
    Locus tag
    Dmel_CG32803
    See related
    AllianceGenome:FB:FBgn0052803
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14819; CG32803; Dmel\CG32803; dmLDAF1
    Summary
    Involved in lipid droplet formation and regulation of lipid storage. Located in lipid droplet. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ldaf1 in Genome Data Viewer
    Location:
    2B14-2B15; 1-0.2 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (1900699..1901911, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (1794726..1795944, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Cytochrome c oxidase assembly factor 8 Neighboring gene trithorax-related Neighboring gene mitochondrial ribosomal protein L16 Neighboring gene armadillo Neighboring gene antisense RNA:CR45929 Neighboring gene antisense RNA:CR43864 Neighboring gene uncharacterized protein Neighboring gene ER degradation enhancer, mannosidase alpha-like 1 Neighboring gene Myb-interacting protein 130

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CG32803 is the fly homolog of LDAF1 and influences lipid storage in vivo. Chartschenko E, et al. Insect Biochem Mol Biol, 2021 Jun. PMID 33307187
    2. The Drosophila MSL complex activates the transcription of target genes. Straub T, et al. Genes Dev, 2005 Oct 1. PMID 16204179, Free PMC Article
    3. RNAseq analysis of the drug jian-yan-ling (JYL) using both in vivo and in vitro models. Zhang X, et al. Heliyon, 2023 May. PMID 37251843, Free PMC Article
    4. Systematic screening of a Drosophila ORF library in vivo uncovers Wnt/Wg pathway components. Schertel C, et al. Dev Cell, 2013 Apr 29. PMID 23583758
    5. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid droplet formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of lipid storage IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in lipid droplet IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lipid droplet assembly factor 1
    Names
    CG32803-PA
    CG32803-PC
    CG32803-PD
    Ldaf1-PA
    Ldaf1-PC
    Ldaf1-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      1900699..1901911 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272222.2 → NP_001259151.1  lipid droplet assembly factor 1, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259151.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PDI7
      Conserved Domains (1) summary
      pfam16015
      Location:77 → 165
      Promethin; Promethin

    2. NM_130601.5 → NP_569957.2  lipid droplet assembly factor 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_569957.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IRW6
      Related
      FBpp0070341
      Conserved Domains (1) summary
      pfam16015
      Location:77 → 171
      Promethin; Promethin

    3. NM_001272221.2 → NP_001259150.1  lipid droplet assembly factor 1, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259150.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PIQ9
      Conserved Domains (1) summary
      pfam16015
      Location:106 → 200
      Promethin; Promethin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PDI7 M9PDI7
    M9PIQ9 M9PIQ9
    Q8IRW6 Q8IRW6
    Q95SA4 Q95SA4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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