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    CG3719 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 44736, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3719provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0024986
    Locus tag
    Dmel_CG3719
    See related
    AllianceGenome:FB:FBgn0024986
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LD03613; Dmel\CG3719; EG:132E8.3
    Summary
    Predicted to be involved in cell redox homeostasis. Predicted to be active in mitochondrion. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; embryonic/larval midgut primordium; larval muscle cell; and mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3719 in Genome Data Viewer
    Location:
    2A1-2A1; 1-0.2 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (1378885..1380480, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (1272918..1274513, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene sister-of-Sex-lethal Neighboring gene mir-4961 stem loop Neighboring gene AMP-activated protein kinase alpha subunit Neighboring gene uncharacterized protein Neighboring gene Rab interacting lysosomal protein like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Thioredoxin-2 affects lifespan and oxidative stress in Drosophila. Svensson MJ, et al. Hereditas, 2007 Mar. PMID 17567437
    2. AMPK supports growth in Drosophila by regulating muscle activity and nutrient uptake in the gut. Bland ML, et al. Dev Biol, 2010 Aug 1. PMID 20478298, Free PMC Article
    3. Mediation of Drosophila autosomal dosage effects and compensation by network interactions. Malone JH, et al. Genome Biol, 2012 Apr 24. PMID 22531030, Free PMC Article
    4. Dynamics of Dark-Fly Genome Under Environmental Selections. Izutsu M, et al. G3 (Bethesda), 2015 Dec 4. PMID 26637434, Free PMC Article
    5. A genomic switch at the transition from cell proliferation to terminal differentiation in the Drosophila eye. Jasper H, et al. Dev Cell, 2002 Oct. PMID 12408803

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in cell redox homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3719-PA
    thioredoxin

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      1378885..1380480 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143733.2 → NP_651990.1  uncharacterized protein Dmel_CG3719 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651990.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76877
      Related
      FBpp0070224
      Conserved Domains (1) summary
      cd02947
      Location:58 → 150
      TRX_family; TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O76877 O76877

    Gene LinkOut

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