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    CG4282 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36825, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG4282provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034114
    Locus tag
    Dmel_CG4282
    See related
    AllianceGenome:FB:FBgn0034114
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4282
    Summary
    Predicted to enable DNA-binding transcription factor activity and transcription cis-regulatory region binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including central brain primordium; ganglia; larval nervous system; and ventral nerve cord primordium. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 10. Orthologous to human ZFP64 (ZFP64 zinc finger protein) and ZNF335 (zinc finger protein 335). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See CG4282 in Genome Data Viewer
    Location:
    53B5-53B5; 2-79 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (16322186..16324801)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (12209691..12212306)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene NADPH oxidase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Vacuolar H[+] ATPase 44kD subunit Neighboring gene HMG Coenzyme A synthase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables transcription cis-regulatory region binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG4282-PA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      16322186..16324801
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137274.4NP_611118.3  uncharacterized protein Dmel_CG4282 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611118.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T092, Q9V7N4
      Related
      FBpp0086288
      Conserved Domains (5) summary
      sd00017
      Location:541562
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:781
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam15909
      Location:389465
      zf-C2H2_8; C2H2-type zinc ribbon
      cl02475
      Location:361400
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      cl19417
      Location:191268
      FYDLN_acid; Protein of unknown function (FYDLN_acid)