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    Ugt316A1 UDP-glycosyltransferase family 316 member A1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40079, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ugt316A1provided by FlyBase
    Official Full Name
    UDP-glycosyltransferase family 316 member A1provided by FlyBase
    Primary source
    FLYBASE:FBgn0036842
    Locus tag
    Dmel_CG3797
    See related
    AllianceGenome:FB:FBgn0036842
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3797; Dmel\CG3797; UGT316A1
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1); UGT1A10 (UDP glucuronosyltransferase family 1 member A10); and UGT1A3 (UDP glucuronosyltransferase family 1 member A3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ugt316A1 in Genome Data Viewer
    Location:
    75F6-75F6; 3-45 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19059400..19062816, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19052500..19055916, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44675 Neighboring gene uncharacterized protein Neighboring gene Sideroflexin 2 Neighboring gene Mitogen-activated protein kinase phosphatase 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of the feedback antagonist naked cuticle by Wingless signaling. Chang JL, et al. Dev Biol, 2008 Sep 15. PMID 18585374, Free PMC Article
    2. The UDP-Glycosyltransferase Family in Drosophila melanogaster: Nomenclature Update, Gene Expression and Phylogenetic Analysis. Ahn SJ, et al. Front Physiol, 2021. PMID 33815151, Free PMC Article
    3. Functional and phylogenetic analyses of a putative Drosophila melanogaster UDP-glycosyltransferase gene. Luque T, et al. Insect Biochem Mol Biol, 2002 Dec. PMID 12429111
    4. Computation-based discovery of related transcriptional regulatory modules and motifs using an experimentally validated combinatorial model. Halfon MS, et al. Genome Res, 2002 Jul. PMID 12097338, Free PMC Article
    5. Comparative analysis of the UDP-glycosyltransferase multigene family in insects. Ahn SJ, et al. Insect Biochem Mol Biol, 2012 Feb. PMID 22155036

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables UDP-glycosyltransferase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycosylation ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UDP-glycosyltransferase family 316 member A1
    Names
    CG3797-PA
    CG3797-PB
    Ugt316A1-PA
    Ugt316A1-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      19059400..19062816 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300182.1 → NP_001287111.1  UDP-glycosyltransferase family 316 member A1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287111.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VVW2
      Conserved Domains (2) summary
      PHA03392
      Location:1 → 480
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      TIGR01426
      Location:39 → 448
      MGT; glycosyltransferase, MGT family

    2. NM_140828.3 → NP_649085.1  UDP-glycosyltransferase family 316 member A1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649085.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VVW2
      Related
      FBpp0074804
      Conserved Domains (2) summary
      PHA03392
      Location:1 → 480
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      TIGR01426
      Location:39 → 448
      MGT; glycosyltransferase, MGT family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VVW2 Q9VVW2

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