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    PEX17 Pex17p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855507, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PEX17
    Official Full Name
    Pex17p
    Primary source
    SGD:S000005158
    Locus tag
    YNL214W
    See related
    AllianceGenome:SGD:S000005158; FungiDB:YNL214W; VEuPathDB:YNL214W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    PAS9
    Summary
    Involved in protein import into peroxisome matrix, docking. Located in peroxisomal membrane. Part of peroxisomal importomer complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See PEX17 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (245617..246216)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene DNA-binding transcription factor RAP1 Neighboring gene Ies2p Neighboring gene Rrg9p Neighboring gene Vid27p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Towards the molecular architecture of the peroxisomal receptor docking complex. Lill P, et al. Proc Natl Acad Sci U S A, 2020 Dec 29. PMID 33323485, Free PMC Article
    2. Pex17p of Saccharomyces cerevisiae is a novel peroxin and component of the peroxisomal protein translocation machinery. Huhse B, et al. J Cell Biol, 1998 Jan 12. PMID 9425153, Free PMC Article
    3. Pex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery. Girzalsky W, et al. J Biol Chem, 2006 Jul 14. PMID 16679311
    4. Pex14p, a peroxisomal membrane protein binding both receptors of the two PTS-dependent import pathways. Albertini M, et al. Cell, 1997 Apr 4. PMID 9094717
    5. Distinct Pores for Peroxisomal Import of PTS1 and PTS2 Proteins. Montilla-Martinez M, et al. Cell Rep, 2015 Dec 15. PMID 26673321

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Both, Pex14p and Pex17p interact directly with Dyn2p, but in vivo, Pex17p turned out to be prerequisite for an association of Dyn2p with Pex14p.
      Title: Pex17p-dependent assembly of Pex14p/Dyn2p-subcomplexes of the peroxisomal protein import machinery.
    2. Pex19p has a role in targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery
      Title: Pex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein import into peroxisome matrix, docking IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of peroxisomal importomer complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in peroxisomal membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in peroxisomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in peroxisomal membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Pex17p
    NP_014185.1
    • Membrane peroxin of the peroxisomal importomer complex; complex facilitates the import of peroxisomal matrix proteins; required for peroxisome biogenesis

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      245617..246216
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183052.1 → NP_014185.1  TPA: Pex17p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014185.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0X6, P40155
      UniProtKB/TrEMBL
      A6ZRM6, B3LP58, B5VQJ8, C7GPE3, G2WLP9, N1NX91
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40155.1

    Gene LinkOut

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