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    MNE1 Mne1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854532, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MNE1
    Official Full Name
    Mne1p
    Primary source
    SGD:S000005877
    Locus tag
    YOR350C
    See related
    AllianceGenome:SGD:S000005877; FungiDB:YOR350C; VEuPathDB:YOR350C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in Group I intron splicing and mitochondrial mRNA processing. Located in mitochondrial matrix. Part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MNE1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (992864..994855, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene proline permease PUT4 Neighboring gene Cin1p Neighboring gene serine/threonine protein kinase MEK1 Neighboring gene TFIIH complex subunit TFB6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mne1 is a novel component of the mitochondrial splicing apparatus responsible for processing of a COX1 group I intron in yeast. Watts T, et al. J Biol Chem, 2011 Mar 25. PMID 21257754, Free PMC Article
    2. Genome-wide association across Saccharomyces cerevisiae strains reveals substantial variation in underlying gene requirements for toxin tolerance. Sardi M, et al. PLoS Genet, 2018 Feb. PMID 29474395, Free PMC Article
    3. Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation. Measday V, et al. Proc Natl Acad Sci U S A, 2005 Sep 27. PMID 16172405, Free PMC Article
    4. Transfer of the Septin Ring to Cytokinetic Remnants in ER Stress Directs Age-Sensitive Cell-Cycle Re-entry. Chao JT, et al. Dev Cell, 2019 Oct 21. PMID 31564614, Free PMC Article
    5. A visual screen of protein localization during sporulation identifies new components of prospore membrane-associated complexes in budding yeast. Lam C, et al. Eukaryot Cell, 2014 Mar. PMID 24390141, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Mne1 is a novel component of the mitochondrial splicing apparatus responsible for processing of a COX1 group I intron in yeast.
      Title: Mne1 is a novel component of the mitochondrial splicing apparatus responsible for processing of a COX1 group I intron in yeast.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in Group I intron splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in Group I intron splicing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitochondrial mRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in mitochondrial matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    part_of ribonucleoprotein complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Mne1p
    NP_014995.1
    • Protein involved in splicing Group I aI5-beta intron from COX1 mRNA; mitochondrial matrix protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      992864..994855 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183770.1 → NP_014995.1  TPA: Mne1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014995.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W345, P24720
      UniProtKB/TrEMBL
      A6ZPI0, C7GNR8, N1NX21
      Conserved Domains (1) summary
      pfam13762
      Location:368 → 516
      MNE1; Mitochondrial splicing apparatus component
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P24720.2

    Gene LinkOut

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