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    Tspyl1 testis-specific protein, Y-encoded-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 22110, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tspyl1provided by MGI
    Official Full Name
    testis-specific protein, Y-encoded-like 1provided by MGI
    Primary source
    MGI:MGI:1298395
    See related
    Ensembl:ENSMUSG00000047514 AllianceGenome:MGI:1298395
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tspyl
    Summary
    Predicted to enable chromatin binding activity; enzyme binding activity; and histone binding activity. Predicted to be involved in nucleosome assembly. Predicted to be located in chromatin; nucleolus; and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Human ortholog(s) of this gene implicated in gonadal dysgenesis and sudden infant death syndrome. Orthologous to several human genes including TSPYL1 (TSPY like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Tspyl1 in Genome Data Viewer
    Location:
    10 B1; 10 18.85 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (34158186..34160881)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (34282190..34284885)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene dermatan sulfate epimerase Neighboring gene STARR-seq mESC enhancer starr_26265 Neighboring gene predicted gene, 18346 Neighboring gene STARR-seq mESC enhancer starr_26267 Neighboring gene predicted gene, 26564 Neighboring gene STARR-seq mESC enhancer starr_26272 Neighboring gene STARR-positive B cell enhancer ABC_E8330 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:34001757-34001940 Neighboring gene STARR-positive B cell enhancer ABC_E3882 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:34017128-34017331 Neighboring gene TSPY-like 4 Neighboring gene 5'-nucleotidase domain containing 1 Neighboring gene STARR-seq mESC enhancer starr_26275 Neighboring gene collagen, type X, alpha 1

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables enzyme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in nucleosome assembly IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    testis-specific Y-encoded-like protein 1
    Names
    TSPY-like 1
    TSPY-like protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009433.3NP_033459.1  testis-specific Y-encoded-like protein 1

      See identical proteins and their annotated locations for NP_033459.1

      Status: VALIDATED

      Source sequence(s)
      AC113059, AK053812, BY281503
      Consensus CDS
      CCDS23777.1
      UniProtKB/Swiss-Prot
      O88852, Q3TKW0
      Related
      ENSMUSP00000063051.6, ENSMUST00000061372.7
      Conserved Domains (1) summary
      cl08298
      Location:174351
      NAP; Nucleosome assembly protein (NAP)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      34158186..34160881
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)