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    Atp5mj ATP synthase membrane subunit j [ Mus musculus (house mouse) ]

    Gene ID: 70257, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Atp5mjprovided by MGI
    Official Full Name
    ATP synthase membrane subunit jprovided by MGI
    Primary source
    MGI:MGI:1917507
    See related
    Ensembl:ENSMUSG00000021290 AllianceGenome:MGI:1917507
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MLQ; Mp68; Atp5mpl; 2010107E04Rik; 9430003J03Rik
    Summary
    Located in mitochondrion. Orthologous to human ATP5MJ (ATP synthase membrane subunit j). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in liver E14 (RPKM 37.9), liver E18 (RPKM 32.3) and 25 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Atp5mj in Genome Data Viewer
    Location:
    12 F1; 12 61.14 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (111927808..111933443, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (111961374..111967009, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 5033406O09 gene Neighboring gene predicted gene, 36757 Neighboring gene STARR-positive B cell enhancer ABC_E8504 Neighboring gene tudor domain containing 9 Neighboring gene retinal degeneration 3-like Neighboring gene predicted gene, 46381

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Evaluation of TRAP-sequencing technology with a versatile conditional mouse model. Hupe M, et al. Nucleic Acids Res, 2014 Jan. PMID 24165879, Free PMC Article
    2. Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy. McLelland GL, et al. Elife, 2018 Apr 20. PMID 29676259, Free PMC Article
    3. Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry. Schweppe DK, et al. Proc Natl Acad Sci U S A, 2017 Feb 14. PMID 28130547, Free PMC Article
    4. The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes. Liu F, et al. Mol Cell Proteomics, 2018 Feb. PMID 29222160, Free PMC Article
    5. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    part_of proton-transporting ATP synthase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of proton-transporting ATP synthase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    ATP synthase subunit ATP5MJ, mitochondrial
    Names
    6.8 kDa mitochondrial proteolipid protein
    ATP synthase membrane subunit 6.8PL
    ATP synthase subunit ATP5MPL, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001361914.1 → NP_001348843.1  ATP synthase subunit ATP5MJ, mitochondrial

      Status: VALIDATED

      Source sequence(s)
      AC132623
      Consensus CDS
      CCDS36566.1
      UniProtKB/Swiss-Prot
      P56379
      UniProtKB/TrEMBL
      A0A1Y7VLP0
      Related
      ENSMUSP00000152618.2, ENSMUST00000222874.2
      Conserved Domains (1) summary
      pfam08039
      Location:1 → 58
      Mit_proteolip; Mitochondrial proteolipid

    2. NM_027360.3 → NP_081636.1  ATP synthase subunit ATP5MJ, mitochondrial

      See identical proteins and their annotated locations for NP_081636.1

      Status: VALIDATED

      Source sequence(s)
      AC132623, AK008333, BB618895
      Consensus CDS
      CCDS36566.1
      UniProtKB/Swiss-Prot
      P56379
      UniProtKB/TrEMBL
      A0A1Y7VLP0
      Related
      ENSMUSP00000021719.6, ENSMUST00000021719.7
      Conserved Domains (1) summary
      pfam08039
      Location:1 → 58
      Mit_proteolip; Mitochondrial proteolipid

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      111927808..111933443 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P56379.1 GenPept UniProtKB/Swiss-Prot:P56379

    Gene LinkOut

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