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    Wdr53 WD repeat domain 53 [ Mus musculus (house mouse) ]

    Gene ID: 68980, updated on 9-Dec-2024

    Summary

    Official Symbol
    Wdr53provided by MGI
    Official Full Name
    WD repeat domain 53provided by MGI
    Primary source
    MGI:MGI:1916230
    See related
    Ensembl:ENSMUSG00000022787 AllianceGenome:MGI:1916230
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1500002B03Rik
    Summary
    Orthologous to human WDR53 (WD repeat domain 53). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 11.0), CNS E11.5 (RPKM 4.5) and 24 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Wdr53 in Genome Data Viewer
    Location:
    16 B2; 16 22.47 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (32066047..32075901)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (32247227..32257085)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene brain expressed family member 6 Neighboring gene STARR-seq mESC enhancer starr_40648 Neighboring gene STARR-seq mESC enhancer starr_40649 Neighboring gene F-box protein 45 Neighboring gene STARR-positive B cell enhancer ABC_E10901 Neighboring gene predicted gene, 25848 Neighboring gene STARR-positive B cell enhancer ABC_E4166 Neighboring gene microRNA 1946a Neighboring gene single-pass membrane protein with coiled-coil domains 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General protein information

    Preferred Names
    WD repeat-containing protein 53

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001185162.2NP_001172091.1  WD repeat-containing protein 53

      See identical proteins and their annotated locations for NP_001172091.1

      Status: VALIDATED

      Source sequence(s)
      AC126265
      Consensus CDS
      CCDS28118.1
      UniProtKB/Swiss-Prot
      Q9DB94
      Related
      ENSMUSP00000135908.2, ENSMUST00000178573.8
      Conserved Domains (3) summary
      COG2319
      Location:237358
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:1349
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:8269
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    2. NM_001399294.1NP_001386223.1  WD repeat-containing protein 53

      Status: VALIDATED

      Source sequence(s)
      AC126265
      UniProtKB/Swiss-Prot
      Q9DB94
      Conserved Domains (3) summary
      COG2319
      Location:237358
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:1349
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:8269
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    3. NM_026898.3NP_081174.1  WD repeat-containing protein 53

      See identical proteins and their annotated locations for NP_081174.1

      Status: VALIDATED

      Source sequence(s)
      AC126265
      Consensus CDS
      CCDS28118.1
      UniProtKB/Swiss-Prot
      Q9DB94
      Related
      ENSMUSP00000023474.4, ENSMUST00000023474.4
      Conserved Domains (3) summary
      COG2319
      Location:237358
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:1349
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:8269
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      32066047..32075901
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)