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    Dnajc5g DnaJ heat shock protein family (Hsp40) member C5 gamma [ Mus musculus (house mouse) ]

    Gene ID: 231098, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dnajc5gprovided by MGI
    Official Full Name
    DnaJ heat shock protein family (Hsp40) member C5 gammaprovided by MGI
    Primary source
    MGI:MGI:3045263
    See related
    Ensembl:ENSMUSG00000053856 AllianceGenome:MGI:3045263
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4922503E23Rik
    Summary
    Is expressed in brain; genitourinary system; and submandibular gland. Orthologous to human DNAJC5G (DnaJ heat shock protein family (Hsp40) member C5 gamma). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 67.7) See more
    Orthologs
    human all
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    Genomic context

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    See Dnajc5g in Genome Data Viewer
    Location:
    5 B1; 5 17.03 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (31265637..31269870)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (31108293..31112526)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38601 Neighboring gene solute carrier family 30 (zinc transporter), member 3 Neighboring gene predicted gene 9924 Neighboring gene STARR-seq mESC enhancer starr_12766 Neighboring gene tripartite motif-containing 54 Neighboring gene predicted gene 15469 Neighboring gene urocortin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. Sundberg JP, et al. PLoS One, 2017. PMID 28700664, Free PMC Article
    2. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    3. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Homology

    Clone Names

    • MGC107182

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    dnaJ homolog subfamily C member 5G
    Names
    DnaJ (Hsp40) homolog, subfamily C, member 5 gamma

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347324.1 → NP_001334253.1  dnaJ homolog subfamily C member 5G isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks two alternate exons compared to variant 1, that causes a frameshift. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AC109608
      Consensus CDS
      CCDS84862.1
      UniProtKB/TrEMBL
      A0A087WQK2
      Related
      ENSMUSP00000144137.2, ENSMUST00000201740.4

    2. NM_177677.3 → NP_808345.1  dnaJ homolog subfamily C member 5G isoform 1

      See identical proteins and their annotated locations for NP_808345.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK076638
      Consensus CDS
      CCDS19172.1
      UniProtKB/TrEMBL
      Q8C632
      Related
      ENSMUSP00000064587.2, ENSMUST00000066544.5
      Conserved Domains (2) summary
      COG0484
      Location:16 → 86
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      pfam00226
      Location:17 → 79
      DnaJ; DnaJ domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      31265637..31269870
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011240723.2 → XP_011239025.1  dnaJ homolog subfamily C member 5G isoform X1

      Conserved Domains (1) summary
      COG0484
      Location:16 → 86
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein Strain
    Heading Accession and Version

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