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    PF3D7_1252200 chitinase [ Plasmodium falciparum 3D7 ]

    Gene ID: 811552, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1252200
    Gene description
    chitinase
    Locus tag
    PF3D7_1252200
    See related
    PlasmoDB:PF3D7_1252200; VEuPathDB:PF3D7_1252200
    Gene type
    protein coding
    RNA name
    chitinase
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1252200 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    1
    Sequence:
    Chromosome: 12; NC_037284.1 (2125435..2126571)

    Chromosome 12 - NC_037284.1Genomic Context describing neighboring genes Neighboring gene tRNA-Gln Neighboring gene rhoptry neck protein 3 Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037284.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Disruption of Plasmodium falciparum chitinase markedly impairs parasite invasion of mosquito midgut. Tsai YL, et al. Infect Immun, 2001 Jun. PMID 11349075, Free PMC Article
    2. The chitinase PfCHT1 from the human malaria parasite Plasmodium falciparum lacks proenzyme and chitin-binding domains and displays unique substrate preferences. Vinetz JM, et al. Proc Natl Acad Sci U S A, 1999 Nov 23. PMID 10570198, Free PMC Article
    3. Characterisation of Plasmodium invasive organelles; an ookinete microneme proteome. Lal K, et al. Proteomics, 2009 Mar. PMID 19206106, Free PMC Article
    4. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables chitin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables chitinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within chitin catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within symbiont entry into host IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in microneme IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    chitinase
    XP_001350904.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037284.1 Reference assembly

      Range
      2125435..2126571
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001350868.1 → XP_001350904.1  chitinase [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001350904.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q8I4R4, Q9U4I9
      UniProtKB/TrEMBL
      A0A024V4Z3, A0A024VPE2, A0A024W3K9, A0A024WL61, A0A024X3B6, A0A0L7KI22, A0A2I0BZ67, W4ICF5, W4J0G7, W7EX35, W7FRK8, W7J8Y9
      Conserved Domains (1) summary
      pfam00704
      Location:55 → 292
      Glyco_hydro_18; Glycosyl hydrolases family 18
    Nucleotide Protein
    Heading Accession and Version

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