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    Rbis ribosomal biogenesis factor [ Mus musculus (house mouse) ]

    Gene ID: 69126, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rbisprovided by MGI
    Official Full Name
    ribosomal biogenesis factorprovided by MGI
    Primary source
    MGI:MGI:1916376
    See related
    Ensembl:ENSMUSG00000078784 AllianceGenome:MGI:1916376
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1810022K09Rik
    Summary
    Predicted to be involved in ribosome biogenesis. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleolus. Orthologous to human RBIS (ribosomal biogenesis factor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in CNS E14 (RPKM 23.0), CNS E11.5 (RPKM 20.0) and 18 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Rbis in Genome Data Viewer
    Location:
    3 A1; 3 3.11 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (14671349..14676419, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (14606289..14611256, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene leucine rich repeat and coiled-coil domain containing 1 Neighboring gene E2F transcription factor 5 Neighboring gene STARR-positive B cell enhancer ABC_E2065 Neighboring gene STARR-seq mESC enhancer starr_07000 Neighboring gene STARR-seq mESC enhancer starr_07001 Neighboring gene predicted gene, 54191 Neighboring gene STARR-seq mESC enhancer starr_07003 Neighboring gene carbonic anhydrase 13

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in ribosome biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosome biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ribosome biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ribosomal biogenesis factor
    Names
    uncharacterized protein C8orf59 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099674.1NP_001093144.1  ribosomal biogenesis factor isoform 2

      See identical proteins and their annotated locations for NP_001093144.1

      Status: VALIDATED

      Source sequence(s)
      AK007585, BC055766, BC100487
      Consensus CDS
      CCDS79886.1
      UniProtKB/Swiss-Prot
      G3UW58, Q0VG62
      Related
      ENSMUSP00000139512.2, ENSMUST00000185384.7
      Conserved Domains (1) summary
      pfam15679
      Location:197
      DUF4665; Domain of unknown function (DUF4665)
    2. NM_001347206.1NP_001334135.1  ribosomal biogenesis factor isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC140350, BC115807
      Consensus CDS
      CCDS84610.1
      UniProtKB/Swiss-Prot
      Q0VG62
      Related
      ENSMUSP00000104002.3, ENSMUST00000108365.4
      Conserved Domains (1) summary
      pfam15679
      Location:43139
      DUF4665; Domain of unknown function (DUF4665)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      14671349..14676419 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319707.3XP_017175196.1  ribosomal biogenesis factor isoform X1

      Conserved Domains (1) summary
      pfam15679
      Location:43119
      DUF4665; Domain of unknown function (DUF4665)