U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Tomm22 translocase of outer mitochondrial membrane 22 [ Mus musculus (house mouse) ]

    Gene ID: 223696, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tomm22provided by MGI
    Official Full Name
    translocase of outer mitochondrial membrane 22provided by MGI
    Primary source
    MGI:MGI:2450248
    See related
    Ensembl:ENSMUSG00000022427 AllianceGenome:MGI:2450248
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tom22; 2310047D01
    Summary
    Predicted to enable mitochondrion targeting sequence binding activity and protein transmembrane transporter activity. Predicted to be involved in positive regulation of apoptotic process; protein insertion into mitochondrial membrane; and protein insertion into mitochondrial outer membrane. Located in mitochondrial inner membrane. Is expressed in genitourinary system. Orthologous to human TOMM22 (translocase of outer mitochondrial membrane 22). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 96.9), placenta adult (RPKM 50.2) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Tomm22 in Genome Data Viewer
    Location:
    15 E1; 15 37.85 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (79555069..79557063)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (79670868..79672862)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 227, member A Neighboring gene STARR-seq mESC enhancer starr_39191 Neighboring gene STARR-seq mESC enhancer starr_39193 Neighboring gene predicted gene, 30877 Neighboring gene chibby family member 1, beta catenin antagonist Neighboring gene Josephin domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E389 Neighboring gene GTP binding protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables mitochondrion targeting sequence binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mitochondrion targeting sequence binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mitochondrial import receptor subunit TOM22 homolog
    Names
    translocase of outer membrane 22 kDa subunit homolog
    translocase of outer mitochondrial membrane 22 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172609.3NP_766197.2  mitochondrial import receptor subunit TOM22 homolog

      See identical proteins and their annotated locations for NP_766197.2

      Status: PROVISIONAL

      Source sequence(s)
      AK009868
      Consensus CDS
      CCDS27646.1
      UniProtKB/Swiss-Prot
      Q543M4, Q9CPQ3, Q9D8D3
      UniProtKB/TrEMBL
      Q3UBW3
      Related
      ENSMUSP00000023062.4, ENSMUST00000023062.5

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      79555069..79557063
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)