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    V1ra8 vomeronasal 1 receptor, A8 [ Mus musculus (house mouse) ]

    Gene ID: 113850, updated on 27-Nov-2024

    Summary

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    Official Symbol
    V1ra8provided by MGI
    Official Full Name
    vomeronasal 1 receptor, A8provided by MGI
    Primary source
    MGI:MGI:2148513
    See related
    Ensembl:ENSMUSG00000062546 AllianceGenome:MGI:2148513
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Vmn1r-ps33
    Summary
    Predicted to enable signaling receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and response to pheromone. Predicted to act upstream of or within sensory perception of chemical stimulus. Predicted to be located in plasma membrane. Orthologous to human VN1R17P (vomeronasal 1 receptor 17 pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See V1ra8 in Genome Data Viewer
    Location:
    6 D1; 6 40.05 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (90179799..90180638)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (90202817..90203656)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 1 receptor, pseudogene 32 Neighboring gene vomeronasal 1 receptor 52 Neighboring gene vomeronasal 1 receptor 53 Neighboring gene TSR1 20S rRNA accumulation pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Deficient pheromone responses in mice lacking a cluster of vomeronasal receptor genes. Del Punta K, et al. Nature, 2002 Sep 5. PMID 12214233
    2. Upregulation of μ3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway. Steinmetz CC, et al. Cell Rep, 2016 Sep 6. PMID 27568566, Free PMC Article
    3. Sequence diversity and genomic organization of vomeronasal receptor genes in the mouse. Del Punta K, et al. Genome Res, 2000 Dec. PMID 11116090, Free PMC Article
    4. Multiple new and isolated families within the mouse superfamily of V1r vomeronasal receptors. Rodriguez I, et al. Nat Neurosci, 2002 Feb. PMID 11802169
    5. Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome. Amid C, et al. BMC Genomics, 2009 Dec 15. PMID 20003482, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables pheromone receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables signaling receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to pheromone IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sensory perception of chemical stimulus TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    vomeronasal type-1 receptor A8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053223.1 → NP_444453.1  vomeronasal type-1 receptor A8

      See identical proteins and their annotated locations for NP_444453.1

      Status: PROVISIONAL

      Source sequence(s)
      AF291487
      Consensus CDS
      CCDS20354.1
      UniProtKB/Swiss-Prot
      B9EHS8, Q9EQ48
      Related
      ENSMUSP00000077479.5, ENSMUST00000078371.6
      Conserved Domains (1) summary
      pfam03402
      Location:39 → 262
      V1R; Vomeronasal organ pheromone receptor family, V1R

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      90179799..90180638
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_015364.1: Suppressed sequence

      Description
      NG_015364.1: This RefSeq was permanently suppressed because it is now thought that this gene is not a pseudogene.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9EQ48.1 GenPept UniProtKB/Swiss-Prot:Q9EQ48

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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