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    Fbxw21 F-box and WD-40 domain protein 21 [ Mus musculus (house mouse) ]

    Gene ID: 320082, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fbxw21provided by MGI
    Official Full Name
    F-box and WD-40 domain protein 21provided by MGI
    Primary source
    MGI:MGI:2443323
    See related
    Ensembl:ENSMUSG00000047237 AllianceGenome:MGI:2443323
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    E330009P21Rik
    Summary
    Predicted to be active in cytoplasm. Is expressed in oocyte and ovary. Orthologous to human FBXW12 (F-box and WD repeat domain containing 12). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Fbxw21 in Genome Data Viewer
    Location:
    9 F2; 9 59.63 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (108968522..108991090, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (109139454..109162022, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1794 Neighboring gene coiled-coil domain containing 51 Neighboring gene predicted gene 7628 Neighboring gene plexin B1 Neighboring gene STARR-seq mESC enhancer starr_25230 Neighboring gene STARR-seq mESC enhancer starr_25231 Neighboring gene F-box and WD-40 domain protein 13 Neighboring gene F-box and WD-40 domain protein 20

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Ovarian gene expression in the absence of FIGLA, an oocyte-specific transcription factor. Joshi S, et al. BMC Dev Biol, 2007 Jun 13. PMID 17567914, Free PMC Article
    2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    F-box domain containing protein
    Names
    novel gene (E330009P21Rik)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001382229.1 → NP_001369158.1  F-box domain containing protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      CT025696
      UniProtKB/TrEMBL
      Q3UWS5
      Related
      ENSMUSP00000143095.2, ENSMUST00000198076.5
      Conserved Domains (2) summary
      COG2319
      Location:109 → 323
      WD40; WD40 repeat [General function prediction only]
      pfam12937
      Location:5 → 46
      F-box-like

    2. NM_177069.3 → NP_796043.1  F-box domain containing protein isoform 1

      See identical proteins and their annotated locations for NP_796043.1

      Status: VALIDATED

      Source sequence(s)
      AK087710
      Consensus CDS
      CCDS23547.1
      UniProtKB/TrEMBL
      Q8BI38
      Related
      ENSMUSP00000056358.7, ENSMUST00000054925.13
      Conserved Domains (3) summary
      COG2319
      Location:109 → 323
      WD40; WD40 repeat [General function prediction only]
      pfam12937
      Location:5 → 48
      F-box-like; F-box-like
      sd00039
      Location:151 → 184
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      108968522..108991090 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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