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    USP2 ubiquitin specific peptidase 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 522980, updated on 30-Jan-2025

    Summary

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    Official Symbol
    USP2provided by VGNC
    Official Full Name
    ubiquitin specific peptidase 2provided by VGNC
    Primary source
    VGNC:VGNC:54894
    See related
    BGD:BT28895; EnsemblRapid:ENSBTAG00070034940
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See USP2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (29935379..29961014, complement)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene C1q and TNF related 5 Neighboring gene ring finger protein 26 Neighboring gene uncharacterized LOC101903835 Neighboring gene membrane frizzled-related protein Neighboring gene Thy-1 cell surface antigen Neighboring gene microRNA mir-378b

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC137635

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 2
    Names
    41 kDa ubiquitin-specific protease
    deubiquitinating enzyme 2
    ubiquitin thioesterase 2
    ubiquitin thiolesterase 2
    ubiquitin-specific-processing protease 2
    NP_001039728.1
    XP_024831053.1
    XP_024831054.1
    XP_059730729.1
    XP_059730730.1
    XP_059730731.1
    XP_059730732.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046263.1 → NP_001039728.1  ubiquitin carboxyl-terminal hydrolase 2

      See identical proteins and their annotated locations for NP_001039728.1

      Status: PROVISIONAL

      Source sequence(s)
      BC112866
      UniProtKB/Swiss-Prot
      Q2KHV7
      UniProtKB/TrEMBL
      A0A3Q1MXE5
      Related
      ENSBTAP00070047869.1, ENSBTAT00070078609.1
      Conserved Domains (1) summary
      pfam00443
      Location:268 → 597
      UCH; Ubiquitin carboxyl-terminal hydrolase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      29935379..29961014 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059874746.1 → XP_059730729.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

      UniProtKB/Swiss-Prot
      Q2KHV7
      UniProtKB/TrEMBL
      A0A3Q1MXE5

    2. XM_059874747.1 → XP_059730730.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

      UniProtKB/Swiss-Prot
      Q2KHV7
      UniProtKB/TrEMBL
      A0A3Q1MXE5

    3. XM_024975285.2 → XP_024831053.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

      UniProtKB/Swiss-Prot
      Q2KHV7
      UniProtKB/TrEMBL
      A0A3Q1MXE5
      Conserved Domains (1) summary
      pfam00443
      Location:268 → 597
      UCH; Ubiquitin carboxyl-terminal hydrolase

    4. XM_059874748.1 → XP_059730731.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X2

      UniProtKB/TrEMBL
      A0AAA9TNR1

    5. XM_024975286.2 → XP_024831054.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1ME39, A0AAA9RVB7
      Related
      ENSBTAP00070047862.1, ENSBTAT00070078590.1
      Conserved Domains (1) summary
      pfam00443
      Location:58 → 387
      UCH; Ubiquitin carboxyl-terminal hydrolase

    6. XM_059874749.1 → XP_059730732.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X4

      UniProtKB/TrEMBL
      A0AAA9TNR1
      Related
      ENSBTAP00070047887.1, ENSBTAT00070078655.1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2KHV7.1 GenPept UniProtKB/Swiss-Prot:Q2KHV7

    Gene LinkOut

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    Research Materials