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    MATN2 matrilin 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 781953, updated on 30-Jan-2025

    Summary

    Official Symbol
    MATN2provided by VGNC
    Official Full Name
    matrilin 2provided by VGNC
    Primary source
    VGNC:VGNC:31265
    See related
    EnsemblRapid:ENSBTAG00070008966
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    See MATN2 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 14 NC_037341.1 (66186819..66359746, complement)

    Chromosome 14 - NC_037341.1Genomic Context describing neighboring genes Neighboring gene glutamate rich 5 Neighboring gene small nucleolar RNA SNORA72 Neighboring gene ribosomal protein L30 Neighboring gene uncharacterized LOC112449541 Neighboring gene U6 spliceosomal RNA Neighboring gene lysosomal protein transmembrane 4 beta Neighboring gene transfer RNA glutamine (anticodon CUG)

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    General gene information

    Markers

    Clone Names

    • MGC139110

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102528.1NP_001095998.1  matrilin-2 precursor

      See identical proteins and their annotated locations for NP_001095998.1

      Status: PROVISIONAL

      Source sequence(s)
      BC140516
      UniProtKB/TrEMBL
      A0AAA9S6L9, A5D7D5, F1MHR8
      Related
      ENSBTAP00070011969.1, ENSBTAT00070020239.1
      Conserved Domains (4) summary
      cd01475
      Location:56278
      vWA_Matrilin; VWA_Matrilin: In cartilaginous plate, extracellular matrix molecules mediate cell-matrix and matrix-matrix interactions thereby providing tissue integrity. Some members of the matrilin family are expressed specifically in developing cartilage rudiments. ...
      pfam10393
      Location:913955
      Matrilin_ccoil; Trimeric coiled-coil oligomerization domain of matrilin
      pfam14670
      Location:408443
      FXa_inhibition; Coagulation Factor Xa inhibitory site
      cl00057
      Location:654894
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037341.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      66186819..66359746 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005215629.3XP_005215686.1  matrilin-2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9S6L9
      Conserved Domains (4) summary
      cd01475
      Location:56278
      vWA_Matrilin; VWA_Matrilin: In cartilaginous plate, extracellular matrix molecules mediate cell-matrix and matrix-matrix interactions thereby providing tissue integrity. Some members of the matrilin family are expressed specifically in developing cartilage rudiments. ...
      pfam10393
      Location:894936
      Matrilin_ccoil; Trimeric coiled-coil oligomerization domain of matrilin
      pfam14670
      Location:408443
      FXa_inhibition; Coagulation Factor Xa inhibitory site
      cl00057
      Location:654875
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...