Fibcd1 fibrinogen C domain containing 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Fibcd1provided by RGD
Full Name: fibrinogen C domain containing 1provided by RGD
Primary source: RGD:1309097
See related: EnsemblRapid:ENSRNOG00000009735 AllianceGenome:RGD:1309097
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Fibcd1l1; RGD1309097
Summary: Predicted to enable chitin binding activity. Predicted to be located in membrane. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Orthologous to human FIBCD1 (fibrinogen C domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 27.2) See more
Orthologs: human mouse all
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Genomic context

Location:: 3p12

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (35490459..35524142, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (15092682..15126371, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (9365866..9399578)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

UniSTS:234369 (e-PCR)
- UniSTS:234369

BF403370 (e-PCR)
- UniSTS:246431

BE097502 (e-PCR)
- UniSTS:244681

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables chitin binding	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in collagen-containing extracellular matrix	IBA Inferred from Biological aspect of Ancestor more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: fibrinogen C domain-containing protein 1

Names: fibrinogen C domain containing 1-like 1; fibrinogen C domain-containing protein 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001107829.2 → NP_001101299.1 fibrinogen C domain-containing protein 1

See identical proteins and their annotated locations for NP_001101299.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/TrEMBL

A6JU32, D4ADA1

Related

ENSRNOP00000012928.5, ENSRNOT00000012927.8

Conserved Domains (1) summary

cd00087
Location:239 → 455

FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...