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    Mogat1 monoacylglycerol O-acyltransferase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363261, updated on 27-Nov-2024

    Summary

    Official Symbol
    Mogat1provided by RGD
    Official Full Name
    monoacylglycerol O-acyltransferase 1provided by RGD
    Primary source
    RGD:1311644
    See related
    EnsemblRapid:ENSRNOG00000014692 AllianceGenome:RGD:1311644
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable 2-acylglycerol O-acyltransferase activity and diacylglycerol O-acyltransferase activity. Predicted to be involved in diacylglycerol biosynthetic process and triglyceride biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human MOGAT1 (monoacylglycerol O-acyltransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 12.6), Brain (RPKM 8.6) and 4 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Mogat1 in Genome Data Viewer
    Location:
    9q33
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (87429427..87436977)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (79980963..79988513)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (84405481..84418657)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene sphingosine-1-phosphate phosphatase 2 Neighboring gene phenylalanyl-tRNA synthetase subunit beta Neighboring gene uncharacterized LOC134480390 Neighboring gene U3 small nucleolar RNA-associated protein 14 homolog B-like Neighboring gene acyl-CoA synthetase long-chain family member 3 Neighboring gene potassium voltage-gated channel subfamily E regulatory subunit 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables 2-acylglycerol O-acyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables diacylglycerol O-acyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables diacylglycerol O-acyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in diacylglycerol biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within diacylglycerol biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glycerol metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in triglyceride biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    2-acylglycerol O-acyltransferase 1
    NP_001102273.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108803.1NP_001102273.1  2-acylglycerol O-acyltransferase 1

      See identical proteins and their annotated locations for NP_001102273.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474004
      UniProtKB/TrEMBL
      A6JW64, D4A6J3
      Related
      ENSRNOP00000019724.4, ENSRNOT00000019724.6
      Conserved Domains (1) summary
      cl17185
      Location:1126
      LPLAT; Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      87429427..87436977
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)