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    tre-3 Trehalase [ Caenorhabditis elegans ]

    Gene ID: 179604, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tre-3
    Official Full Name
    Trehalase
    Primary source
    WormBase:WBGene00006609
    Locus tag
    CELE_W05E10.4
    See related
    AllianceGenome:WB:WBGene00006609
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable alpha,alpha-trehalase activity. Predicted to be involved in trehalose catabolic process. Located in membrane raft. Is expressed in several structures, including head; intestine; rectal gland cell; reproductive system; and tail. Orthologous to human TREH (trehalase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tre-3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    11
    Sequence:
    Chromosome: V; NC_003283.11 (11709769..11715903, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Receptor-type guanylate cyclase daf-11;guanylate cyclase Neighboring gene Ammonium transporter AmtB-like domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Origins of recently gained introns in Caenorhabditis. Coghlan A, et al. Proc Natl Acad Sci U S A, 2004 Aug 3. PMID 15243155, Free PMC Article
    2. Trehalose metabolism genes in Caenorhabditis elegans and filarial nematodes. Pellerone FI, et al. Int J Parasitol, 2003 Sep 30. PMID 13678635
    3. An analysis of the Caenorhabditis elegans lipid raft proteome using geLC-MS/MS. Rao W, et al. J Proteomics, 2011 Feb 1. PMID 21070894
    4. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
    5. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables alpha,alpha-trehalase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables alpha,alpha-trehalase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, acting on glycosyl bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in trehalose catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in trehalose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane raft HDA PubMed 

    General protein information

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    Preferred Names
    Trehalase
    NP_001256361.1
    • Confirmed by transcript evidence
    NP_001256362.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      11709769..11715903 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001269432.3 → NP_001256361.1  Trehalase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256361.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F5GUD3, G5EG27
      Conserved Domains (1) summary
      cl17346
      Location:40 → 560
      Trehalase; Trehalase

    2. NM_001269433.3 → NP_001256362.1  Trehalase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256362.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F5GUD4
      Conserved Domains (1) summary
      cl17346
      Location:3 → 49
      Trehalase; Trehalase
    Nucleotide Protein
    Heading Accession and Version

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