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    capg-1 Condensin complex subunit capg-1 [ Caenorhabditis elegans ]

    Gene ID: 172521, updated on 9-Dec-2024

    Summary

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    Official Symbol
    capg-1
    Official Full Name
    Condensin complex subunit capg-1
    Primary source
    WormBase:WBGene00009254
    Locus tag
    CELE_F29D11.2
    See related
    AllianceGenome:WB:WBGene00009254
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in embryo development; meiotic sister chromatid segregation; and mitotic sister chromatid segregation. Part of dosage compensation complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See capg-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    14
    Sequence:
    Chromosome: I; NC_003279.8 (7634492..7639785, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Low-density lipoprotein receptor-related protein Neighboring gene ncRNA Neighboring gene Lipid droplet-associated hydrolase Neighboring gene Nuclear cap-binding protein subunit 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Difference in phenotypic severity of presumed null alleles of capg-1. VanDiepenbos S, et al. MicroPubl Biol, 2020 May 10. PMID 32550486, Free PMC Article
    2. Condensin I protects meiotic cohesin from WAPL-1 mediated removal. Hernandez MR, et al. PLoS Genet, 2018 May. PMID 29768402, Free PMC Article
    3. Condensins regulate meiotic DNA break distribution, thus crossover frequency, by controlling chromosome structure. Mets DG, et al. Cell, 2009 Oct 2. PMID 19781752, Free PMC Article
    4. Two classes of dosage compensation complex binding elements along Caenorhabditis elegans X chromosomes. Blauwkamp TA, et al. Mol Cell Biol, 2009 Apr. PMID 19188444, Free PMC Article
    5. Three distinct condensin complexes control C. elegans chromosome dynamics. Csankovszki G, et al. Curr Biol, 2009 Jan 13. PMID 19119011, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that condensin I binds to WAPL-1 and counteracts WAPL-1-dependent cohesin removal.
      Title: Condensin I protects meiotic cohesin from WAPL-1 mediated removal.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chromosome condensation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in embryo development ending in birth or egg hatching IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in meiotic sister chromatid segregation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitotic chromosome condensation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic chromosome condensation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitotic sister chromatid segregation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in mitotic sister chromatid segregation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in condensed chromosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of condensin complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of dosage compensation complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Condensin complex subunit capg-1
    NP_492128.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7634492..7639785 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059727.6 → NP_492128.1  Condensin complex subunit capg-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492128.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      G5EFJ4
      Conserved Domains (2) summary
      cl25751
      Location:1075 → 1147
      DUF4045; Domain of unknown function (DUF4045)
      cl26312
      Location:718 → 977
      Cnd3; Nuclear condensing complex subunits, C-term domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    G5EFJ4.1

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