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    C06A5.8 RING-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172276, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C06A5.8
    Official Full Name
    RING-type domain-containing protein
    Primary source
    WormBase:WBGene00015505
    Locus tag
    CELE_C06A5.8
    See related
    AllianceGenome:WB:WBGene00015505
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Is expressed in germ line and oocyte. Orthologous to human RNF227 (ring finger protein 227). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C06A5.8 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (6008137..6009524, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene NAD-dependent protein deacetylase sir-2.4 Neighboring gene Tropomodulin Neighboring gene LEM-like domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene RING-type domain-containing protein Neighboring gene Integrator complex subunit 1 RPB2-binding domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Shifted Transversal Design smart-pooling for high coverage interactome mapping. Xin X, et al. Genome Res, 2009 Jul. PMID 19447967, Free PMC Article
    2. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RING-type domain-containing protein
    NP_001379541.1
    • Confirmed by transcript evidence
    NP_491737.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      6008137..6009524 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059336.6 → NP_491737.1  RING-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491737.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01481
      Conserved Domains (3) summary
      cd00162
      Location:38 → 83
      RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
      cl00414
      Location:123 → 185
      bS6; Bacterial ribosomal protein S6
      cl17238
      Location:38 → 84
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    2. NM_001392389.1 → NP_001379541.1  RING-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86ND0
      Conserved Domains (1) summary
      cl00414
      Location:55 → 117
      bS6; Bacterial ribosomal protein S6
    Nucleotide Protein
    Heading Accession and Version

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