mif-3 MIF-like protein mif-3 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: mif-3
Official Full Name: MIF-like protein mif-3
Primary source: WormBase:WBGene00003236
Locus tag: CELE_F13G3.9
See related: AllianceGenome:WB:WBGene00003236
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable cytokine activity and phenylpyruvate tautomerase activity. Involved in regulation of lipid storage and regulation of peptide transport. Located in nucleus. Is expressed in body wall musculature; intestine; pharyngeal muscle cell; and reproductive system. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See mif-3 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 3

Sequence:: Chromosome: I; NC_003279.8 (7312797..7313525, complement)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

no association between G/C polymorphism at promoter gene of MIF and the incidence of pulmonary hamartoma
Title: The -173 G/C polymorphism of the promoter region macrophage migration inhibitory factor gene is not associated with incidence of pulmonary hamartoma.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F13G3.10 (e-PCR)
- UniSTS:315729

F13G3.9 (e-PCR)
- UniSTS:315730

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables cytokine activity	IBA Inferred from Biological aspect of Ancestor more info
enables phenylpyruvate tautomerase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of lipid storage	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of peptide transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: MIF-like protein mif-3

NP_492069.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

7312797..7313525 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_059668.4 → NP_492069.1 MIF-like protein mif-3 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_492069.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P90835

Conserved Domains (1) summary

cl00235
Location:2 → 113

4Oxalocrotonate_Tautomerase; 4-Oxalocrotonate Tautomerase: Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one ...