pipp-4P Phosphatidylinositol-4,5-bisphosphate 4-phosphatase [Caenorhabditis elegans] - Gene

Summary

Official Symbol: pipp-4P
Official Full Name: Phosphatidylinositol-4,5-bisphosphate 4-phosphatase
Primary source: WormBase:WBGene00022167
Locus tag: CELE_Y71H2AM.2
See related: AllianceGenome:WB:WBGene00022167
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation. Predicted to be located in endosome; lysosome; and membrane. Predicted to be active in bounding membrane of organelle and plasma membrane. Orthologous to human PIP4P1 (phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1) and PIP4P2 (phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in phosphatidylinositol dephosphorylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in phosphatidylinositol dephosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endosome	IEA Inferred from Electronic Annotation more info
is_active_in late endosome membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in late endosome membrane	IEA Inferred from Electronic Annotation more info
is_active_in lysosomal membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in lysosomal membrane	IEA Inferred from Electronic Annotation more info
located_in lysosome	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in phagocytic vesicle membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

NP_001411904.1

NP_497624.3

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The following sections contain reference sequences that belong to a specific genome build. Explain

NM_001424978.1 → NP_001411904.1 Phosphatidylinositol-4,5-bisphosphate 4-phosphatase [Caenorhabditis elegans]

Status: REVIEWED
NM_065223.6 → NP_497624.3 Phosphatidylinositol-4,5-bisphosphate 4-phosphatase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_497624.3

Status: REVIEWED

UniProtKB/TrEMBL

Q9BL29

Conserved Domains (1) summary

pfam09788
Location:59 → 217

Tmemb_55A; Transmembrane protein 55A