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    sup-10 Putative potassium channel regulatory protein sup-10 [ Caenorhabditis elegans ]

    Gene ID: 181784, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sup-10
    Official Full Name
    Putative potassium channel regulatory protein sup-10
    Primary source
    WormBase:WBGene00006319
    Locus tag
    CELE_R09G11.1
    See related
    AllianceGenome:WB:WBGene00006319
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables potassium channel regulator activity. Involved in regulation of muscle contraction and regulation of potassium ion transport. Located in plasma membrane and striated muscle dense body. Is expressed in anal depressor muscle; body wall musculature; head neurons; intestinal muscle; and vulval muscle. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sup-10 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    6
    Sequence:
    Chromosome: X; NC_003284.9 (17528344..17531985)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA Neighboring gene Nuclear hormone receptor family member nhr-1;Nuclear receptor domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of revertants of unc-93(e1500) in Caenorhabditis elegans induced by N-ethyl-N-nitrosourea. De Stasio E, et al. Genetics, 1997 Oct. PMID 9335597, Free PMC Article
    2. A visible allele of the muscle gene sup-10X of C. elegans. Greenwald I, et al. Genetics, 1986 May. PMID 3710144, Free PMC Article
    3. sup-9, sup-10, and unc-93 may encode components of a two-pore K+ channel that coordinates muscle contraction in Caenorhabditis elegans. de la Cruz IP, et al. J Neurosci, 2003 Oct 8. PMID 14534247, Free PMC Article
    4. Functions of the Caenorhabditis elegans regulatory myosin light chain genes mlc-1 and mlc-2. Rushforth AM, et al. Genetics, 1998 Nov. PMID 9799259, Free PMC Article
    5. The Caenorhabditis elegans iodotyrosine deiodinase ortholog SUP-18 functions through a conserved channel SC-box to regulate the muscle two-pore domain potassium channel SUP-9. de la Cruz IP, et al. PLoS Genet, 2014 Feb. PMID 24586202, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables potassium channel regulator activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in potassium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of muscle contraction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of potassium ion transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in striated muscle dense body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Putative potassium channel regulatory protein sup-10
    NP_510835.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      17528344..17531985
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078434.7 → NP_510835.1  Putative potassium channel regulatory protein sup-10 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510835.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q17374, Q21879
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q17374.2

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