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    tbc-14 Rab-GAP TBC domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174986, updated on 9-Dec-2024

    Summary

    Official Symbol
    tbc-14
    Official Full Name
    Rab-GAP TBC domain-containing protein
    Primary source
    WormBase:WBGene00008444
    Locus tag
    CELE_E01G4.1
    See related
    AllianceGenome:WB:WBGene00008444
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable GTPase activator activity. Predicted to be located in cytoplasm. Orthologous to human TBC1D15 (TBC1 domain family member 15) and TBC1D17 (TBC1 domain family member 17). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See tbc-14 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    8
    Sequence:
    Chromosome: II; NC_003280.10 (13436923..13447593, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Carnosine N-methyltransferase Neighboring gene SnoaL-like domain-containing protein Neighboring gene ncRNA Neighboring gene MIF4G domain-containing protein;Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables GTPase activator activity  
    Component Evidence Code Pubs
    located_in cytoplasm  

    General protein information

    Preferred Names
    Rab-GAP TBC domain-containing protein
    NP_001317775.1
    • Confirmed by transcript evidence
    NP_001317776.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      13436923..13447593 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001330963.2NP_001317775.1  Rab-GAP TBC domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A168H1X0
      Conserved Domains (2) summary
      smart00164
      Location:318553
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      pfam12068
      Location:51195
      DUF3548; Domain of unknown function (DUF3548)
    2. NM_001330964.4NP_001317776.1  Rab-GAP TBC domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A164D380
      Conserved Domains (2) summary
      smart00164
      Location:320555
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      pfam12068
      Location:51197
      DUF3548; Domain of unknown function (DUF3548)
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