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    lys-4 LYSozyme [ Caenorhabditis elegans ]

    Gene ID: 178086, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lys-4
    Official Full Name
    LYSozyme
    Primary source
    WormBase:WBGene00003093
    Locus tag
    CELE_F58B3.1
    See related
    AllianceGenome:WB:WBGene00003093
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable lysozyme activity. Involved in defense response to Gram-positive bacterium. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lys-4 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    2
    Sequence:
    Chromosome: IV; NC_003282.8 (11621429..11623174, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Delta-like protein Neighboring gene ncRNA Neighboring gene Lysozyme-like protein 5 Neighboring gene LYSozyme

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables lysozyme activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell wall macromolecule catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in defense response to Gram-positive bacterium IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in peptidoglycan catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to stress IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    LYSozyme
    NP_502192.1
    • Product from WormBase gene class lys;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      11621429..11623174 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069791.9 → NP_502192.1  LYSozyme [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502192.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20964
      Conserved Domains (1) summary
      cd06416
      Location:19 → 212
      GH25_Lys1-like; Lys-1 is a lysozyme encoded by the Caenorhabditis elegans lys-1 gene. This gene is one of a several lysozyme genes upregulated upon infection by the Gram-negative bacterial pathogen Serratia marcescens. Lys-1 contains a glycosyl hydrolase family 25 ...
    Nucleotide Protein
    Heading Accession and Version

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