mdt-29 Mediator of RNA polymerase II transcription subunit 29 [Caenorhabditis elegans] - Gene

Summary

Go to the top of the page Help

Official Symbol: mdt-29
Official Full Name: Mediator of RNA polymerase II transcription subunit 29
Primary source: WormBase:WBGene00007025
Locus tag: CELE_K08E3.8
See related: AllianceGenome:WB:WBGene00007025
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Involved in lateral inhibition; positive regulation of Notch signaling pathway; and regulation of cell fate specification. Predicted to be located in nucleus. Predicted to be part of mediator complex. Is expressed in body wall musculature. [provided by Alliance of Genome Resources, Dec 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See mdt-29 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 7

Sequence:: Chromosome: III; NC_003281.10 (13773456..13778889)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

3R5.2 (e-PCR)
- UniSTS:321879

K08E3.7 (e-PCR)
- UniSTS:313237

K08E3.8 (e-PCR)
- UniSTS:313238

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in lateral inhibition	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of Notch signaling pathway	IGI Inferred from Genetic Interaction more info	PubMed
involved_in regulation of cell fate specification	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
part_of mediator complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: Mediator of RNA polymerase II transcription subunit 29

NP_499847.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

13773456..13778889

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_067446.8 → NP_499847.1 Mediator of RNA polymerase II transcription subunit 29 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_499847.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9XUS2

Conserved Domains (2) summary

pfam11568
Location:294 → 434

Med29; Mediator complex subunit 29

cl18951
Location:208 → 319

Amidase; Amidase