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    Y39E4B.6 IK cytokine;Smad nuclear-interacting protein 1 [ Caenorhabditis elegans ]

    Gene ID: 176728, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y39E4B.6
    Official Full Name
    IK cytokine;Smad nuclear-interacting protein 1
    Primary source
    WormBase:WBGene00012717
    Locus tag
    CELE_Y39E4B.6
    See related
    AllianceGenome:WB:WBGene00012717
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable 7SK snRNA binding activity and cyclin-dependent protein serine/threonine kinase inhibitor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y39E4B.6 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (13070756..13074305)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene CX domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Palmitoyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables 7SK snRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cyclin-dependent protein serine/threonine kinase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cyclin-dependent protein serine/threonine kinase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables snRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    IK cytokine;Smad nuclear-interacting protein 1
    NP_001380120.1
    • Confirmed by transcript evidence
    NP_499710.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      13070756..13074305
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067309.7 → NP_499710.1  Smad nuclear-interacting protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499710.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U2K4
      Conserved Domains (1) summary
      pfam15313
      Location:69 → 187
      HEXIM; Hexamethylene bis-acetamide-inducible protein

    2. NM_001392222.1 → NP_001380120.1  IK cytokine [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      I2HAG3
      Conserved Domains (1) summary
      pfam15313
      Location:40 → 175
      HEXIM; Hexamethylene bis-acetamide-inducible protein
    Nucleotide Protein
    Heading Accession and Version

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